A Case of Atransferrinemia and 35 Cases of Hypotransferrinemia As Determined by Radioassay of Total Iron-binding Capacity of the Serum

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  • SAITO Hiroshi
    Department of Radiology, Nagoya University School of Medicine

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Other Title
  • 総血清鉄結合能 (TIBC) のradioassayにより発見された低トランスフェリン血症35例と，無トランスフェリン血症の1例について
  • ソウ ケッセイ テツ ケツゴウノウ TIBC ノ radioassay ニ ヨ

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Description

Total iron-binding capacity of the serum (TIBC) was determined by radioassay method developed by Saito.<br>Fifty μg/dl (38 mg/dl as transferrin) of TIBC, which is as low as in the cases of congenital atransferrinemia was found in a patient having a high plasma RISA disappearance rate. A similar ferrokinetics pattern was observed between the present case and the cases of congenital atransferrinemia.<br>In addition, 35 cases of hypotransferrinemia having TIBC less than 200 μg/dl were found in 600 determinations: 60% in 35 cases were blood diseases, 37% were malignancies, 20% were the diseases of digestive organs, including 2 cases of protein losing gastroenteropathy.<br>The radioassay method of TIBC was very useful for clinical transferrin assay.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 16 (11), 1036-1043, 1975

    The Japanese Society of Hematology

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