食道癌，肺癌を合併したSézary症候群の1例

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タイトル別名
  • Small Cell Variant Sézary's Syndrome with Esophageal and Lung Carcinoma
  • 食道癌,肺癌を合併したSezary症候群の1例
  • ショクドウガン ハイガン オ ガッペイシタ Sezary ショウコウグン ノ

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The Patient was a 78-year-old man. He was admitted to our hospital because of cough, sputum and slight fever. A pruritic erythroderma began about five years before. On physical examination, pigmented erythroderma, leonine face and lymphadenopathy were recognized. The peripheral leukocyte count was 26,100 per cmm with 75% abnormal lymphoid cells. Bone marrow was normal. Abnormal lymphoid cells were confirmed to have T cell properties with E rosette-forming method. In electron microscopic studies of peripheral blood and skin, the abnormal cells were 7-15μ in diameter. The nucleus was indented and serpentine. These cells had pseudodiploid chromosome numbers with B marker chromosome. A diagnosis of small cell variant Sézary's syndrome was made. The bronchograhy and bronchoscopy including biopsies revealed the complication of lung carcinoma. Six years ago, he had recieved radiation therapy for esophageal carcinoma. The combination chemotherapy with prednisolone, adriamycin and carboquone was not effective. He died of cachexia in 98 days after the admission.

収録刊行物

  • 臨床血液

    臨床血液 23 (3), 340-348, 1982

    一般社団法人 日本血液学会

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