An autopsy case of von Willebrand's disease died of sudden ovarial hemorrhage

DOI Web Site
  • AMEMIYA Yoichi
    The First Department of Internal Medicine, Nihon University School of Medicine
  • NAGATA Yasuo
    The First Department of Internal Medicine, Nihon University School of Medicine
  • IWANAGA Takayuki
    The First Department of Internal Medicine, Nihon University School of Medicine
  • IKEGUCHI Eikichi
    The First Department of Internal Medicine, Nihon University School of Medicine
  • AMAKI Ichita
    The First Department of Internal Medicine, Nihon University School of Medicine
  • ANDO Morio
    Higashi-Oizumi Hospital

Bibliographic Information

Other Title
  • 突然卵巣出血で死亡したvon Willebrand病の1剖検例
  • トツゼン ランソウ シュッケツ デ シボウ シタ von Willebrandビョウ ノ 1 ボウケンレイ

Search this article

Description

A case of twenty three years old female with hemorrhagic diathesis was diagnosed as von Willebrand's disease in 1967.<br>Bleeding time was 25 minutes, coagulation time, platelet counts and clot retraction were normal, and rate of platelet adhesiveness was 11%.<br>Factor VIII activity was elevated from 5% to 25% after an infusion of AHG concentrate (Cohn fraction I), although the logically expected value was estimated to be 14%.<br>After two and half years of her dismissal from the hospital, she complained of sudden severe abdominal pain and thereafter her vital signs were diminished markedly, and she died on the next day. At autopsy, there was 1000 ml of blood in the abdominal cavity, and some hematomas were found in the bilateral ovaries and retroperitoneal serosa.<br>The massive ovarial hemorrhage probably due to the ovulation seemed to be the direct cause of her death.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 12 (3), 261-265, 1971

    The Japanese Society of Hematology

Details 詳細情報について

Report a problem

Back to top