<i>Plasmodium vivax</i> malaria with clinical presentation mimicking acute type idiopathic thrombocytopenic purpura

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  • KOMODA Minori
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • FUJIMOTO Takeshi
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • KAWAGUCHI Yasuhisa
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • TSUSHIMA Hideki
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • FUKUSHIMA Takuya
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • HATA Tomoko
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • MIYAZAKI Yasushi
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • TSUKASAKI Kunihiro
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences
  • TOMONAGA Masao
    Molecular Medicine Unit Atomic Bomb Disease Institute, Nagasaki University, Graduate School of Biomedical Sciences

Bibliographic Information

Other Title
  • 急性型特発性血小板減少性紫斑病類似の臨床像を呈した三日熱マラリア
  • 症例報告 急性型特発性血小板減少性紫斑病類似の臨床像を呈した三日熱マラリア
  • ショウレイ ホウコク キュウセイガタ トクハツセイ ケッショウバン ゲンショウセイ シハンビョウ ルイジ ノ リンショウゾウ オ テイシタ ミッカ ネツ マラリア

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Abstract

Causes of thrombocytopenia are diverse, and infection with plasmodia often brings about thrombocytopenia. Japan is not an endemic area of malaria infection at present and most cases are travelers to endemic areas. In some cases, initial clinical diagnoses may not be correct because of a variety of symptoms, physical findings and laboratory abnormalities. A 67-year-old female, who had traveled to South American countries 2 months before the onset of the disease, presented with a case of vivax malaria. Because of the patient's high fever, profound thrombocytopenia (1.5×104/μl), and elevated platelet-associated IgG on admission, our initial diagnosis was acute type idiopathic thrombocytopenic purpura (ITP). However, we recognized her tertian fever and plasmodial vivax in erythrocytes 4 days later. She responded promptly to anti-parasitic therapy after diagnosis of malaria and her laboratory data also improved. Travel history is indicative of malaria infection in some cases with thrombocytopenia mimicking acute ITP.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 47 (11), 1453-1456, 2006

    The Japanese Society of Hematology

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