A Retrospective Study of the Length of Hospitalization Following Allogeneic Bone Marrow Transplantation.

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  • MORIYA Akiko
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • MORI Shin-ichiro
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • KAMI Masahiro
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • MATSUMURA Tomoko
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • INOUE Takashi
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • SATO Yoriko
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • NAKANE Minoru
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • OHASHI Kazuteru
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • AKIYAMA Hideki
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • KAKU Hidefumi
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • SASAKI Tsuneo
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • HIRUMA Kiyoshi
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital
  • SAKAMAKI Hisashi
    Hematopoietic Cell Transplantation Team, Tokyo Metropolitan Komagome Hospital

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Other Title
  • 同種骨髄移植症例の入院期間の検討
  • ドウシュ コツズイ イショク ショウレイ ノ ニュウイン キカン ノ ケントウ

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Abstract

To estimate the length of hospitalization following bone marrow transplantation (BMT), we conducted a retrospective study of 190 patients who had received allogeneic BMTs at our institution. By our criteria, patients were considered ready for discharge if they were afebrile, did not need intravenous chemotherapy or blood transfusions more than 2 times per week, had maintained these conditions for 1 week or more, and also had no medical history of hepatic veno-occlusive disease, grade-II-or-higher graft-versus-host disease, interstitial pneumonitis, or severe hepato-renal dysfunction. The median length of hospitalization was 108.5 days. Of 82 patients who satisfied our discharge criteria by their 70th hospital day, 10 experienced mild complications during the next 30 hospital days. Of 89 patients who were considered ready for discharge by the 40th hospital day, 30 and 38 experienced complications during the next 30 and 60 hospital days, respectively, and 16 required emergency treatment. No significant baseline characteristics distinguished the patients who experienced complications from those who did not, either after 40 or 70 hospital days. This compounded the difficulty of predicting the development of complications in patients who satisfied our discharge criteria. Although management on an outpatient basis should be safe and feasible for BMT patients who meet our discharge criteria by the 70th day of hospitalization, caution is advised for early discharges after only 40 hospital days.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 41 (1), 12-19, 2000

    The Japanese Society of Hematology

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