Pediatric acute lymphoblastic leukemia initially presenting with bone marrow necrosis

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  • KATO Motohiro
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • KIKUCHI Akira
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • OSHIMA Koichi
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • YAMAMOTO Syohei
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • MOCHIZUKI Shinji
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • ARAI Kokoro
    Saitama Children's Medical Center, The Department of Hematology/Oncology
  • HANADA Ryoji
    Saitama Children's Medical Center, The Department of Hematology/Oncology

Bibliographic Information

Other Title
  • 広汎な骨髄壊死を初発症状として発症した小児急性リンパ性白血病
  • 症例報告 広汎な骨髄壊死を初発症状として発症した小児急性リンパ性白血病
  • ショウレイ ホウコク コウハン ナ コツズイ エシ オ ショハツ ショウジョウ ト シテ ハッショウ シタ ショウニ キュウセイ リンパセイ ハッケツビョウ

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Abstract

We report on a case of pediatric acute lymphoblastic leukemia presenting with massive bone marrow necrosis. A 4-year-old boy complained of fever and leg pain. Laboratory data revealed pancytopenia, but bone marrow examination showed only necrotic materials. About one month later, repeated bone marrow examination showed leukemic cells and the necrotic marrow had disappeared. The patient was treated with standard chemotherapy and was successfully induced to complete remission. Patients with massive bone marrow necrosis should undergo bone marrow examination repeatedly to make the correct diagnosis.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 48 (2), 140-143, 2007

    The Japanese Society of Hematology

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