Bilateral internal carotid artery occlusion and severe basilar artery stenosis in a patient with fibromuscular dysplasia: a case report

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Other Title
  • 線維筋形成不全により両側内頸動脈閉塞と脳底動脈の高度狭窄をきたした1例
  • 症例報告 線維筋形成不全により両側内頸動脈閉塞と脳底動脈の高度狭窄をきたした1例
  • ショウレイ ホウコク センイキン ケイセイ フゼン ニ ヨリ リョウガワ ナイ ケイドウミャク ヘイソク ト ノウテイ ドウミャク ノ コウド キョウサク オ キタシタ 1レイ

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Abstract

Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory arterial disease of unknown etiology. We report a 26-year-old woman who presented with transient ischemic attack (TIA) due to bilateral internal carotid artery (ICA) occlusion and severe basilar artery stenosis, as FMD was diagnosed by a biopsy specimen of right ICA. Imaging investigations included magnetic resonance angiography and catheter angiogram without characteristic “string of beads" pattern, before reaching a definitive diagnosis by pathologist. Anti-platelet therapy and bypass surgery of superficial temporal artery-middle cerebral artery revealed no more clinical symptoms. This case of intra- and extra-cranial FMD gives a consideration of such rare disease in the differential diagnosis of TIA or stroke in healthy young patients. The literature of FMD is reviewed including pathological findings.

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 53 (6), 439-445, 2013

    Societas Neurologica Japonica

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