A case of acute cerebellar ataxia associated with serum anti-NH2 terminal of alpha-enolase (NAE) antibody
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- Yamamoto Mikie
- Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University
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- Wada-Isoe Kenji
- Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University
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- Yoneda Makoto
- Second Department of Internal Medicine (Neurology), Faculty of Medical Sciences, University of Fukui
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- Doi Koji
- Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University
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- Kowa Hisanori
- Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University
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- Nakashima Kenji
- Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University
Bibliographic Information
- Other Title
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- 抗N末端α-エノラーゼ抗体をみとめた急性小脳失調症の1例
- コウN マッタン アルファ エノラーゼ コウタイ オ ミトメタ キュウセイ ショウノウ シッチョウショウ ノ 1レイ
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Description
We reported a 61-year-old man who had developed acute cerebellar ataxia in the trunk and the lower limbs. His chemical blood analysis showed very mild hypothyroidism and the presence of serum anti-thyroid peroxidase (TPO) antibody and anti-NH2 terminal of alpha-enolase (NAE) antibody. While cerebellar atrophy was not evident on magnetic resonance imaging (MRI) of the brain, 99mTc-ECD SPECT using the easy Z-score imaging system (e-ZIS) showed decreased regional cerebral blood flow (rCBF) in the vermis of cerebellum. His cerebellar ataxia improved spontaneously within three weeks. The present case is very rare and suggests that anti-NAE autoantibody may be associated with actue cerebellar ataxia.<br>
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 50 (8), 581-584, 2010
Societas Neurologica Japonica
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Details 詳細情報について
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- CRID
- 1390001205034973312
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- NII Article ID
- 130004504788
- 10027705681
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- NII Book ID
- AN00253207
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- ISSN
- 18820654
- 0009918X
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- NDL BIB ID
- 10808458
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- PubMed
- 20803969
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed