多彩な前駆症状を伴い発症したHemopoietic Dysplasiaの1症例

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タイトル別名
  • A Case of Hemopoietic Dysplasia Accompanied with Various Prodromal Symptoms
  • タサイ ナ ゼンク ショウジョウ オ トモナイ ハッショウシタ Hemopoi

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抄録

A case of hemopoietic dysplasia or acute myeloproliferative disorder was reported.<br>Recently, the incidence of atypical leukemia has been increased especially at the aged population. Furthermore, the clinical nomenclature of atypical leukemia has been confused and overlapped. Since hemopoietic dysplasia can be recognized as those diseases which are not distinguishable from leukemia on the clinical and hematological findings, the proliferative ability of the abnormal hematological clones was considered to be so promoted in this case that the series of gradual loss of differentiation ability was not observed until the death due to diffuse infiltration with the abnormal cells into many organs.<br>Although the relationship between the abnormal immunological findings and the expression of hemopoietic dysplasia is not clear at present time, the various prodromal symptoms observed in this case are suggestive to the possibilit es that the immunological response of the host to the newly obtained antigens of the abnormal clones or the autoimmune like response of the already altered host lymphocytes.<br>Further studies on immunological aspect of hemopoietic dysplasia are ardently required which may provide a clue to elucidate the etiological mechanism of leukemia itself.

収録刊行物

  • 臨床血液

    臨床血液 20 (12), 1655-1661, 1979

    一般社団法人 日本血液学会

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