Nasal flaring during hypoxemia in myotonic dystrophy and Duchenne muscular dystrophy

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  • Suzuki Mikiya
    Department of Neurology, National Center Hospital of Neurology and Psychiatry Department of Neurology, Higashisaitama National Hospital
  • Oya Yasushi
    Department of Neurology, National Center Hospital of Neurology and Psychiatry
  • Murakami Yoshitake
    Department of Neurology, National Center Hospital of Neurology and Psychiatry
  • Ogawa Masafumi
    Department of Neurology, National Center Hospital of Neurology and Psychiatry
  • Kawai Mitsuru
    Department of Neurology, National Center Hospital of Neurology and Psychiatry Department of Neurology, Higashisaitama National Hospital

Bibliographic Information

Other Title
  • 筋強直性ジストロフィーとＤｕｃｈｅｎｎｅ型筋ジストロフィーの低酸素血症時における鼻翼呼吸
  • キン キョウチョクセイ ジストロフィー ト Duchenneガタ キンジストロフィー ノ テイサンソ ケッショウジ ニ オケル ビヨク コキュウ

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Abstract

We investigated the relationship between nasal flaring and SpO2 in 19 patients with Duchenne muscular dystrophy (DMD) and 26 patients with myotonic dystrophy (DM1). In DMD patients, nasal flaring was observed when SpO2 was lower than 96%, while it was not seen even at 82% of SpO2 in DM1. None of the DM1 patients could perform voluntary nasal flaring. Nasal flaring is a useful indicator of hypoxemia in DMD but not in DM1. It remains to be elucidated whether the lack of nasal flaring in DM1 patients is due to abnormal respiratory central mechanism or nasal muscle weakness.<br>

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 49 (5), 278-280, 2009

    Societas Neurologica Japonica

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