Spontaneous regression of methotrexate-related diffuse large B-cell lymphoma following bladder lesion resection

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  • YAMADA Michiko
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • KURODA Hiroyuki
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • SATO Ken
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • MIURA Shogo
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • AMEDA Saki
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • SAKANO Hiroya
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • SHIBATA Takanori
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • UEMURA Naoki
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • ABE Tomoyuki
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • FUJII Shigeyuki
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • MAEDA Masahiro
    Dept. of Gastroenterology and Hematology/Clinical Oncology, Internal Medicine, Steel Memorial Muroran Hospital
  • FUJITA Miri
    Dept. of Pathology and Clinical Laboratory, Steel Memorial Muroran Hospital
  • KATO Junji
    Dept. of Medical Oncology and Hematology, Internal Medicine, Sapporo Medical University

Bibliographic Information

Other Title
  • 膀胱病変切除を契機に自然消褪したmethotrexate関連びまん性大細胞型B細胞リンパ腫
  • 症例報告 膀胱病変切除を契機に自然消褪したmethotrexate関連びまん性大細胞型B細胞リンパ腫
  • ショウレイ ホウコク ボウコウ ビョウヘン セツジョ オ ケイキ ニ シゼンショウタイシタ methotrexate カンレンビマンセイ ダイ サイボウガタ B サイボウ リンパシュ

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Abstract

<p>A 71-year-old woman who had been treated with methotrexate (MTX) and prednisolone for rheumatoid arthritis since 2010 presented with hematuria. Cystitis was diagnosed. Chest and abdominal CT images revealed a bladder tumor, with lung and bilateral adrenal metastases. Transurethral resection of the bladder tumor (TUR-BT) confirmed these findings in September 2014. Histological findings of the bladder included large atypical lymphoid cells indicating diffuse large B-cell lymphoma. After TUR-BT, CT imaging showed that the tumor had shrunk. Still, MTX was continued. She was diagnosed with MTX-related lymphoproliferative disorders in November 2014 and MTX was discontinued. Fluorodeoxyglucose-positron emission tomography on March 2015 showed a complete response.</p>

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 58 (4), 287-291, 2017

    The Japanese Society of Hematology

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