A case of Legionnaires’ infection with meningeal irritation and abnormal cerebrospinal fluid
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- Hasegawa Juri
- Department of Neurology, Tomishiro Central Hospital
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- Horikawa Tomohumi
- Department of Neurology, Tomishiro Central Hospital Department of Neuropsychiatry, Kurume University School of Medicine
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- Endo Kazuhiro
- Department of Neurology, Tomishiro Central Hospital
Bibliographic Information
- Other Title
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- 髄膜刺激徴候,髄液異常を呈したレジオネラ感染の1例
- 症例報告 髄膜刺激徴候,髄液異常を呈したレジオネラ感染の1例
- ショウレイ ホウコク ズイマク シゲキ チョウコウ,ズイエキ イジョウ オ テイシタ レジオネラ カンセン ノ 1レイ
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Abstract
A 60-year-old man was admitted to our hospital because of fever and mental status change. Neurological examination showed meningeal irritation and frontal sign. Cerebrospinal fluid (CSF) examination showed mild pleocytosis and elevated protein. Laboratory findings showed hyponatremia, elevated liver enzymes and creatine phosphokinase, and positive Legionella pneumophila antigen in urine. The chest computed tomographic scans showed consolidation in the left lower lobe lung. We diagnosed Legionnaires’ pneumonia and started treatment with levofloxacin. Legionella pneumophila was isolated from culture of the bronchoalveolar lavage fluid, but Legionella culture and polymerase chain reaction in CSF were negative. We hypothesize that Legionella pneumophila could produce nerological symptoms by immune-mediated mechanism associated with elevated IgG index. The neurologist should recognize the presence of the meningo-encephalitis associated with Legionnaires’ pneumonia lacking remarkable pulmonary symptoms.
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 53 (7), 526-530, 2013
Societas Neurologica Japonica
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Keywords
Details 詳細情報について
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- CRID
- 1390001205035823616
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- NII Article ID
- 130004505529
- 40019732327
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- NII Book ID
- AN00253207
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- COI
- 1:STN:280:DC%2BC3sfktlahug%3D%3D
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- ISSN
- 18820654
- 0009918X
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- NDL BIB ID
- 024741875
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- PubMed
- 23892963
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed