An adult case of mumps-associated encephalitis/encephalopathy successfully treated with steroid pulse therapy
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- Yamamoto Daisuke
- Department of Neurology, Seirei Hamamatsu General Hospital
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- Uchiyama Tsuyoshi
- Department of Neurology, Seirei Hamamatsu General Hospital
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- Sugiyama Takashi
- Department of Neurology, Seirei Hamamatsu General Hospital
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- Sato Keishiro
- Department of Neurology, Seirei Hamamatsu General Hospital
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- Shimizu Takako
- Department of Neurology, Seirei Hamamatsu General Hospital
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- Ohashi Toshihiko
- Department of Neurology, Seirei Hamamatsu General Hospital
Bibliographic Information
- Other Title
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- ステロイドパルス療法が奏功した成人ムンプス関連性脳炎/脳症の1例
- ステロイドパルス リョウホウ ガ ソウコウ シタ セイジン ムンプス カンレンセイ ノウエン/ノウショウ ノ 1レイ
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Abstract
A 32-year-old-immunologically healthy woman suffered from mumps. A few days later, she was brought to our hospital because of generalized convulsions. On arrival, she developed a decorticate posture. Anti-mumps virus antibodies were detected in her serum. Elevated protein levels without pleocytosis were observed in her cerebrospinal fluid. On the basis of a diagnosis of mumps-associated encephalitis/encephalopathy, steroid pulse therapy was administered, which improve her disturbance of consciousness. She exhibited akinetic mutism, which was followed by deterioration of the frontal lobe. Single-photon emission computed tomography demonstrated decreased regional cerebral blood flow in the bilateral frontal regions. Therefore, she was suspected with frontal lobe dysfunction associated with the lesion, including the thalamus and/or brain stem. We consider that the encephalitis/encephalopathy present in this case was caused by a reversible autoimmune process triggered by mumps virus infection.
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 53 (10), 839-842, 2013
Societas Neurologica Japonica
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Keywords
Details 詳細情報について
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- CRID
- 1390001205036346880
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- NII Article ID
- 130004505314
- 40019827712
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- NII Book ID
- AN00253207
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- COI
- 1:STN:280:DC%2BC2c7mtFGjsQ%3D%3D
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- ISSN
- 18820654
- 0009918X
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- NDL BIB ID
- 024931833
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- PubMed
- 24225570
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed