造血器悪性腫瘍に合併したPneumocystis carinii肺炎の8例

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タイトル別名
  • Eight Cases of Pneumocystis carinii Pneumonitis Associated with Hematological Malignancies
  • ゾウケツキ アクセイ シュヨウ ニ ガッペイシタ Pneumocystis c

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Eight cases of Pneumocystis carinii pneumonitis (PC pneumonitis) associated with hematological malignancies were reported, which were observed at Nagoya National Hospital during the six years ending in January 1977.<br>The patients, aged 17 to 76, were relatively old. The underlying diseases of PC pneumonitis comprised 3 of acute myelogenous leukemia, 4 of malignant lymphoma, and 1 of leukemic reticulosis. Five of them were in remission, and 3 were in exacerbation at the time when PC pneumonitis developed.<br>In all cases, fever was initially present, then severe progressive dyspnea developed. In contrast, physical findings were not so marked.<br>Almost all patients had the history of being treated with large doses of corticosteroids and cytotoxic drugs, which may have exerted an important role in predisposing the patients to PC pneumonitis.<br>The majority of the cases showed negative Mantoux reaction, and patients except for a case of leukemic reticulosis showed continuously decreased count of peripheral lymphocyte for 30 to 40 days, while they did not necessarily have decreased levels of serum gammaglobulin or of specific immunoglobulins.

収録刊行物

  • 臨床血液

    臨床血液 18 (11), 1303-1311, 1977

    一般社団法人 日本血液学会

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