Ischemic stroke under anticoagulant therapy
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- Inoue Yasuteru
- Stroke Center, Saiseikai Kumamoto Hospital
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- Inatomi Yuichiro
- Stroke Center, Saiseikai Kumamoto Hospital
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- Yonehara Toshiro
- Stroke Center, Saiseikai Kumamoto Hospital
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- Hashimoto Yoichiro
- Department of Neurology, Kumamoto City Hospital
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- Hirano Teruyuki
- Department of Neurology, Graduate School of Medical Sciences, Kumamoto University
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- Uchino Makoto
- Department of Neurology, Graduate School of Medical Sciences, Kumamoto University
Bibliographic Information
- Other Title
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- 抗凝固療法中に発症した虚血性脳卒中
- コウギョウコ リョウホウ チュウ ニ ハッショウ シタ キョケツセイ ノウソッチュウ
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Abstract
In order to determine predictive factors of stroke recurrence during anticoagulant therapy and to estimate prognosis, we retrospectively examined clinical data of 197 consecutive patients with acute ischemic stroke. The subjects were divided into two groups, within the therapeutic range group and below therapeutic range group, based on Japanese guidelines for the management of stroke 2004.<br> Univariate analysis revealed that cardioembolic stroke patients were less frequent in the therapeutic range group (61% vs 77%; p=0.03), while more lacunar stroke patients were experienced (17% vs 6%; p=0.01). In patients with past history of cardioembolic stroke, significant favorable outcomes as of Barthel index (54 vs 33; p=0.03) and modified Rankin Scale (3 vs 4; p=0.04) were found within the therapeutic range group. There is a possibility that adequate anticoagulation prevents thrombogenesis or lead to early recanalization, especially in patients with past history of cardioembolic stroke.<br>
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 50 (7), 455-460, 2010
Societas Neurologica Japonica
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Details 詳細情報について
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- CRID
- 1390001205036664064
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- NII Article ID
- 10026525634
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- NII Book ID
- AN00253207
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- ISSN
- 18820654
- 0009918X
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- NDL BIB ID
- 10773605
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed