Basic and Clinical Studies on SPAC Ferritin Kit

DOI Web Site PubMed
  • KURANE Riichi
    Division of Hematology, Department of Medicine, Tokyo Women's Medical College
  • MIYAZAKI Tamotsu
    Division of Hematology, Department of Medicine, Tokyo Women's Medical College
  • WAKATA Asako
    Division of Hematology, Department of Medicine, Tokyo Women's Medical College
  • TAKAHASHI Masatomo
    Division of Hematology, Department of Medicine, Tokyo Women's Medical College

Bibliographic Information

Other Title
  • スパックフェリチンキットの基礎的ならびに臨床的研究
  • スパックフェリチンキット ノ キソテキ ナラビニ リンショウテキ ケンキュウ

Search this article

Description

Kit for serum ferritin assay (SPAC ferritin kit) which was offered by Daiichi Radioisotope Labs. was studied on the basic points and serum ferritin was measured in various hematological diseases. Concerning to the basic points, a reproducibility test, a recovery test and a dilution test were examined. From these results, a good correlation was obtained in each test, however, when the values showed more than 150∼200 ng/ml, a proper dilution and a reexamination should be recommended because of an increasing error.<br>Concerning to the clinical examinations, sera form the normal subjects and the patients with hematological diseases, for example, iron deficiency anemia, aplastic anemia, hemolytic anemia, polycythemia vera, leukemia, multiple myeloma, myelofibrosis and so on were examied. In normal subjects, a significantly higher value in men was shown than in woman. Iron deficiency anemia showed a markedly low value and serum ferritin elevated after an effective treatment. In other hematological dieases, serum ferritin showed various values. Based on these results, it was suggested that they may reflect an iron deficiency state due to a bleeding, a disturbed iron utilization due to an impaired erythropoiesis, an iron overload state due to blood transfusions, a production by leukemia cells, a release from liver cells and so on.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 21 (3), 308-319, 1980

    The Japanese Society of Hematology

Keywords

Details 詳細情報について

Report a problem

Back to top