EFFECTS OF NOREPINEPHRINE ON UPTAKE AND OXIDATION OF PLASMA FREE FATTY ACIDS IN COLD-ACCLIMATED RATS
書誌事項
- タイトル別名
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- Effects of Norepinephrine on Uptake and
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抄録
In order to know the mode of action of norepinephrine in enhanced utilization of plasma free fatty acids (FFA) in cold acclimation, albumin-bound 14C-palmitate was infused intravenously at a constant rate into cold- and warm-acclimated rats under pentobarbital anesthesia with and without norepinephrine infusion. Rectal temperature, CO2 output and plasma FFA, from which the rates of FFA uptake and oxidation were calculated, were determined simultaneously. Similar fractions, that is, 7 and 5%of the total uptake of plasma FFA by the tissue were immediately oxidized in both cold- and warm-acclimated rats, respectively. Norepinephrine infusion caused a significant increase in all the parameters examined. In addition, during hormone infusion the percentage of FFA uptake oxidized was elevated from 22%in control to 50%in coldacclimated rats. This increment was accompanied with greater increases in rectal temperature and CO2 output. Similarly, in functionally eviscerated cold-acclimated rats, norepinephrine induced a greater increase in the percentage of FFA uptake oxidized than in eviscerated controls. These results indicate that although the FFA uptake was increased simultaneously norepinephrine infusion caused a more marked acceleration of the oxidation of plasma FFA in the cold-acclimated rats than in control rats.
収録刊行物
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- The Japanese Journal of Physiology
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The Japanese Journal of Physiology 27 (5), 601-616, 1977
一般社団法人 日本生理学会
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詳細情報 詳細情報について
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- CRID
- 1390001205043263872
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- NII論文ID
- 130003476644
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- NII書誌ID
- AA00691224
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- COI
- 1:CAS:528:DyaE1cXhs1Cluro%3D
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- ISSN
- 18811396
- 0021521X
- http://id.crossref.org/issn/0021521X
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- HANDLE
- 2115/32834
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- NDL書誌ID
- 1910361
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- PubMed
- 604588
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可