Vertical Transmission to Embryo and Fetus in Maternal Infection with Rat Virus (RV).
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- KAJIWARA Noriko
- Laboratory Animal Research Center, University of Tsukuba
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- UENO Yutaka
- Laboratory Animal Research Center, University of Tsukuba
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- TAKAHASHI Akio
- Laboratory Animal Research Center, University of Tsukuba
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- SUGIYAMA Fumihiro
- Laboratory Animal Research Center, University of Tsukuba
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- SUGIYAMA Yoshihiro
- Laboratory Animal Research Center, University of Tsukuba
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- YAGAMI Ken-ichi
- Laboratory Animal Research Center, University of Tsukuba
書誌事項
- タイトル別名
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- Vertical Transmission to Embryo and Fet
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抄録
The influence of maternal rat virus (RV) infection on rat embryogenesis and fetus was examined by viral reisolation, immunostaining and PCR analysis. Vertical transmission caused by the UT-1 strain of RV depended on the stage of gestation when maternal infection occurred. When females were infected at the pre-mating point, the number of fetuses was smaller than that normally obtained, possibly due to infection at the stage of the hatched blastocyst, but almost all of the fetuses obtained were free from infection and developed normally. The incidence of transplacental infection was the highest when pregnant females were infected in the middle of the gestation stage, and some of the fetuses died. In pregnant females which were infected late in the gestation stage, all fetuses developed normally. Some of them were infected transplacentally and harbored the infectious virus. Much attention should be paid to performing reliable rederivation of RV-infected rat colonies by hysterectomy and embryo transfer.<br>
収録刊行物
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- Experimental Animals
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Experimental Animals 45 (3), 239-244, 1996
公益社団法人 日本実験動物学会
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詳細情報 詳細情報について
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- CRID
- 1390001205043378304
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- NII論文ID
- 10007528796
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- NII書誌ID
- AA11032321
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- ISSN
- 18817122
- 00075124
- 13411357
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- NDL書誌ID
- 3997586
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- PubMed
- 8840140
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可