An Epidemiologic Study of Anti-ATLA (Antibody to Adult T-Cell Leukemia-Associated Antigen) by Category of Disease in the Karatsu and Higashimatsuura Districts of Northern Kyusyu by Enzymeimmunoassay
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- MOROFUJI Miki
- The Department of General Medicine, Kyushu University Hospital
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- KAJIYAMA Wataru
- The Department of General Medicine, Kyushu University Hospital
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- NAKASHIMA Koya
- The Department of General Medicine, Kyushu University Hospital
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- NOGUCHI Akinori
- The Department of General Medicine, Kyushu University Hospital
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- HAYASHI Jun
- The Department of General Medicine, Kyushu University Hospital
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- KASHIWAGI Seizaburo
- The Department of General Medicine, Kyushu University Hospital
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- SUMIDA Ikuo
- Karatsu Red Cross Hospital
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- HANADA Motosuke
- Karatsu Red Cross Hospital
Bibliographic Information
- Other Title
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- 唐津, 東松浦地区における疾患別抗ATLA (adult T-cell leukemia-associated antigen) 抗体調査
- カラツ ヒガシ マツウラ チク ニ オケル シッカンベツ コウ ATLA ad
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Description
The Kyusyu district is known as an endemic area of HTLV-I. But the prevalence of anti-ATLA in Saga prefecture was reportedly relatively low.<BR>In this study, in order to determine the distribution of antibody to ATL-associated antigen (anti-ATLA) in the Karatsu and Higashimatsuura districts of the northern Kyusyu, the determination of anti-ATLA status of patients in Karatsu Red Cross Hospital was carried out from September to October, 1985. Sera from 757 patients were tested for presence of anti-ATLA by Enzymeimmunoassay (EIA) prepared by Eisai Co., Ltd. Tokyo, Japan.<BR>Results obtained are as follows:<BR>1) Overall prevalence of anti-ATLA was 13.7 per cent (104 of 757 individuals). Prevalence of anti-ATLA increased with age, reaching a maximum of 21.1 per cent for people from 60 to 69 years old.<BR>2) Prevalence of anti-ATLA was 9.5 per cent (36 of 376) in males and 17.8 per cent (68 of 381) in females. A significant difference by sex was recognized. (p<0.001)<BR>3) The positive rates of patients with non-malignant diseases were high in the Chinzei, Hizen, and Hamatama areas facing the Sea of Genkai. The positive rate of the seaside area was significantly higher than that of the mountain area. (pp<0.001)<BR>4) Anti-ATLA was most prevalent in the patients with neoplasms (26.1%). The positive rate of ATL patients was 100 per cent, and that of patients with malignancies other than ATL was 25.9 per cent.<BR>These results suggest that HTLV-I infection is likely to increase the incidence of other types of malignancy.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 64 (8), 1013-1018, 1990
The Japanese Association for Infectious Diseases
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Details 詳細情報について
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- CRID
- 1390001205045364352
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- NII Article ID
- 130004329695
- 40000567109
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 3683912
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- PubMed
- 1976713
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed