Clinical Studies of Fluconazole in Patients with Deep-Seated Fungal Infection in Intravenous Hyperalimentation (IVH)

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  • TAKEDA Seiji
    The Second Department of Internal Medicine, Fukuoka University School of Medicine
  • TATARA Ichiro
    The Second Department of Internal Medicine, Fukuoka University School of Medicine
  • KONO Kenji
    The Second Department of Internal Medicine, Fukuoka University School of Medicine
  • ARAKAWA Kikuo
    The Second Department of Internal Medicine, Fukuoka University School of Medicine

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Other Title
  • 経静脈高カロリー栄養施行中の深在性真菌症に対するfluconazoleの臨床的検討
  • ケイ ジョウミャク コウ カロリーエイヨウ シコウチュウ ノ シンザイセイ シ

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Abstract

Clinical efficacy of fluconazole on fungal infections was evaluated. Fluconazole was administrated orally or intravenously to 16 cases with fungal infections (chronic renal failure 4, congestive heart failure 2, cerebral infarction 2, etc).<BR>All cases were suspected of mycosis. The details of those administrated were 16 cases of pneumonia 3 cases, fungemia 9 cases (suspected 7 cases) and urinary tract infection 3 cases.<BR>Clinical efficacy rate was 71.4%.<BR>Side-effects were observed in only 1 case, and this consisted of transient increase of leukocytes and thrombocytes.<BR>Fluconazole is considered to be a potent, safe antifungal agent for the treatment of suspected fungal infection during intravenous hyperalimentation.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 70 (5), 437-440, 1996

    The Japanese Association for Infectious Diseases

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