National BioResource Project-Rat and Related Activities

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  • SERIKAWA Tadao
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • MASHIMO Tomoji
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • TAKIZAWA Akiko
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • OKAJIMA Ryoko
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • MAEDOMARI Naoki
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • KUMAFUJI Kenta
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • TAGAMI Fumi
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • NEODA Yuki
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • OTSUKI Mito
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • NAKANISHI Satoshi
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • YAMASAKI Ken-ichi
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • VOIGT Birger
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University
  • KURAMOTO Takashi
    Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University

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Abstract

In order to establish a system to facilitate the systematic collection, preservation, and provision of laboratory rats (Rattus norvegicus) and their derivates, the National BioResource Project-Rat (NBRP-Rat) was launched in July 2002. By the end of 2008, more than 500 rat strains had been collected and preserved as live animals, embryos, or sperm. These rat resources are supplied to biomedical scientists in Japan as well as in other countries. This review article introduces NBRP-Rat and highlights the phenome project, recombinant inbred strains, BAC clone libraries, and the ENU-mutant archive, named the Kyoto University Rat Mutant Archive (KURMA). The future direction of rat resources are also discussed.<br>

Journal

  • Experimental Animals

    Experimental Animals 58 (4), 333-341, 2009

    Japanese Association for Laboratory Animal Science

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