A Pathological Study of Cytomegalovirus Infections in Autopsied Cases with Adult T-Cell Leukemia

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  • 成人T細胞白血病剖検例でのサイトメガロウイルス感染症の病理学的検討
  • セイジン Tサイボウ ハッケツビョウ ボウケンレイ デ ノ サイトメガロ ウイ

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Abstract

In this study, cytomegalovirus (CMV) infection was found in eleven of 21 autopsied cases (52.4%) with adult T-cell leukemia (ATL). Seven cases (63.6%) revealed disseminated infection in more than three organs. The lungs were involved in all eleven cases (100%), adrenal glands in eight cases (72.7%), esophagus in four cases (36.4%), and stomach, small intestine and urinary bladder in three cases (27.3%). Histopathological findings suggested that lung involvement was the cause of death in five of the 11 cases, the small intestine were involved in two of the 3 cases, and the adrenal glands were involved in one of the 8 cases.<BR>In summary, CMV infection was found to be the main cause of death in five (45.5%) of the 11 ATL patients.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 71 (3), 222-228, 1997

    The Japanese Association for Infectious Diseases

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