Outbreak of Hepatitis A Virus Infection among Men Who Have Sex with Men

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  • TAKECHI Akiko
    Department of Internal Medicine, Tokyo Metropolitan Ohkubo Hospital
  • HATAKEYAMA Shuji
    Department of Internal Medicine, Tokyo Metropolitan Ohkubo Hospital
  • KASHIYAMA Tetsuya
    Department of Internal Medicine, Tokyo Metropolitan Ohkubo Hospital
  • KOIBUCHI Tomohiko
    Department of Infectious Disease and Applied Immunology, Institute of Medical Science, University of Tokyo

Bibliographic Information

Other Title
  • 男性同性愛者における急性A型肝炎の流行についての検討
  • ダンセイ ドウ セイアイシャ ニ オケル キュウセイ Aガタ カンエン ノ リュウコウ ニ ツイテ ノ ケントウ

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Abstract

We have recently encountered an outbreak of hepatitis A in Tokyo. Between July 1998 and November 1999, 21 patients were treated at our hospital. They were all male and 18 patients (86%) had had sex with men (MSM). About a half of the patients were seropositive for syphilis, hepatitis B and HIV. The VP1/2A region could be amplified by nested PCR in 6 of the 21 patients. They had the same sequences and were grouped into genotype IA. Homosexual activity should be kept in mind as a leading risk factor for hepatitis A in the recent Japanese population.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 74 (9), 716-719, 2000

    The Japanese Association for Infectious Diseases

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