Report II. Absorption, Excretion, Distribution and Metabolism

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  • Cefmetazoleの吸収, 排泄, 分布, 代謝について
  • Cefmetazole ノ キュウシュウ ハイセツ ブンプ タイシャ ニ ツイ
  • Profile of cefmetazole. II: absorption, excretion, distribution and metabolism [in Japanese]

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Abstract

The results of studies in 32 research institutes in Japan regarding absorption, excretion, distribution and metabolism of cefmetazole are summarized as follows:<BR>After intramuscular injection, one-shot intravenous injection or intravenous drip infusion, cefmetazole is rapidly absorbed and transferred into blood resulting in high blood concentrations and its disappearance from blood is faster than CEZ but slower than CET, somewhere in between these two drugs in the blood concentration half life.<BR>Excretion of cefmetazole into urine is favorable, indicating that it is not metabolized in vivo and the major portion is excreted in urine in unchanged active form.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 53 (2), 66-74, 1979

    The Japanese Association for Infectious Diseases

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