First Case of Tsutsugamushi Disease in Fukui Prefecture with Isolation of Rickettsia from its Donated Blood

TAKADA Nobuhiro, OHTSUKI Norio

doi:10.11150/kansenshogakuzasshi1970.59.496

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献血液よりRickettsiaを分離できた福井県の確実な恙虫病第1例
献血液よりRickettsiaを分離できた福井県の確実な恙虫病第1例
ケンケツエキヨリ Rickettsia オブンリデキタフクイケンノ
First Case of Tsutsugamushi Disease in Fukui Prefecture with Isolation of Rickettsia from its Donated Blood

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The first case of tsutsugamushi desease in Fukui Prefecture which was validly diagnosed was reported with a special notice to the isolation of Rickettsia from its blood donated for a blood donor center. The patient, a 50-year-old male in Takahama, Fukui Pref., began to have chill and fever with a eschar on his left arm on May 28, 1984. He was admitted to the Department of Dermatology of Maizuru Kyosai Hospital, Kyoto Pref. on June 4. Because the extensive roseolar and the eschar suggested tsutsugamushi disease, he was initially treated with Minocycline 200 mg/day for 14 days, and was discharged as recovered clinically on June 18. The elevated titers of serum antibody to rickettsial antigens were observed in Indirect Immunofluorescent and Peroxidase-Labeled Antibody tests during the course. His donated blood was locked up just after the tentative diagnosis, and then a strain of Rickettsia was isolated from the material at the first passage using ddY mouse. The strain was mildly pathogenic, but not yet clarified about the characteristics.

Journal

Kansenshogaku Zasshi

Kansenshogaku Zasshi 59 (5), 496-499, 1985

The Japanese Association for Infectious Diseases

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First Case of Tsutsugamushi Disease in Fukui Prefecture with Isolation of <I>Rickettsia</I> from its Donated Blood