A Case of Infectious Mononucleosis Due to Epstein-Barr Virus with Suspected Reactivation of Human Herpesvirus 6

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  • SHIZUMA Toru
    Department of Internal Medicine, Kikuna Memorial Hospital Department of Physiology, School of Medicine, Tokai University

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Other Title
  • Human herpesvirus 6の再活性化を伴ったEpstein-Barr virusによる伝染性単核症の1例
  • 症例 Human herpesvirus6の再活性化を伴ったEpstein-Barr virusによる伝染性単核症の1例
  • ショウレイ Human herpesvirus 6 ノ サイカッセイカ オ トモナッタ Epstein Barr virus ニ ヨル デンセンセイ タンカクショウ ノ 1レイ

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Abstract

A 24-year-old woman hospitalized with fever, general fatigue, and upper abdominal pain was found to have liver dysfunction and an increase in atypical lymphocytes in peripheral blood. Serum immunological studies showed positive Epstein-Barr virus (EBV) VCA IgM antibody and human herpesvirus 6 (HHV-6) IgM and IgG antibodies, and negative EBV VCA IgG and EBNA antibodies on admission. Liver function was back within normal limits 8 weeks after onset, EBV VCA IgM and IgG antibodies were positive, EBNA and HHV-6 IgM antibodies were negative, and the HHV-6 IgG antibody titer was 8 times higher than that on admission. This case was diagnosed as infectious mononucleosis due to EBV with suspected reactivation of HHV-6.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 82 (1), 47-50, 2008

    The Japanese Association for Infectious Diseases

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