<I>Campylobacter fetus</I> subsp.<I>fetus</I> sepsis: A Case Report and Review of the Literatures in Japan

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  • SAITO Shukuko
    Department of General Medicine, Juntendo University School of Medicine
  • NAITO Toshio
    Department of General Medicine, Juntendo University School of Medicine
  • KUKINO Junko
    Department of General Medicine, Juntendo University School of Medicine
  • OKUMURA Tetsu
    Department of General Medicine, Juntendo University School of Medicine
  • SEKIYA Sakae
    Department of General Medicine, Juntendo University School of Medicine
  • ISONUMA Hiroshi
    Department of General Medicine, Juntendo University School of Medicine
  • WATANABE Kazuyoshi
    Department of General Medicine, Juntendo University School of Medicine
  • DAMBARA Takashi
    Department of General Medicine, Juntendo University School of Medicine
  • HAYASHIDA Yasuo
    Department of General Medicine, Juntendo University School of Medicine

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Other Title
  • 摂食障害による超低体重の女性に発症した<I>Campylobacter fetus</I>敗血症の1例
  • 症例 摂食障害による超低体重の女性に発症したCampylobacter fetus敗血症の1例
  • ショウレイ セッショク ショウガイ ニ ヨル チョウテイタイジュウ ノ ジョセイ ニ ハッショウ シタ Campylobacter fetus ハイケツショウ ノ 1レイ
  • Campylobacter fetus subsp.fetus sepsis: A Case Report and Review of the Literatures in Japan

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Abstract

We report a 32-year-old female with eating disorder whose body weight was only 20kg. She was admitted to the hospital with severe low nutrition, low proteinemia, liver dysfunction, hypokalemia and hypoglycemia. On the third hospital day, she had a high fever and Campylobacter fetus subsp. fetus (C. fetus) was isolated from the blood. After treatment with meropenem (1g/day) intravenous drip injection, her condition improved.<BR>C. fetus sepsis is not common disease in Japan. A review of 37 cases of this disease in Japan revealed that the age range of adult patients was 20 to 60 years old. The male-to-female ratio was 4.6 to 1.0. Seventy-eight percent of the patients had underlying diseases which were composed of 11 patients with liver disease, 6 patients with blood dyscrasia and some with diabetes mellitus, heart disease, other malignant tumor and collagen disease. There was no case with eating disorder. All apparent sources of infection in Japan originate from eating raw food. Gastrointestinal symptoms were observed in only 16% of the patients. Recent recommendations for the treatment of C. fetus sepsis are to use gentamicin, imipenem and meropenem. Some strains of C. fetus have resistance to erythromycin, ciprofloxacin. The mortality of this infection is 14% in Japan.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 78 (1), 70-75, 2004

    The Japanese Association for Infectious Diseases

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