Studies on Tests of In vitro Lymphocyte Transformation to Streptococcal T Antigens in Asthmatic Children

DOI Web Site PubMed

Bibliographic Information

Other Title
  • 小児気管支喘息における溶レン菌T抗原に対する<I>in vitro</I>リンパ球幼若化反応の検討
  • 小児気管支喘息における溶レン菌T抗原に対するin vitroリンパ球幼若化反応の検討
  • ショウニ キカンシ ゼンソク ニ オケル ヨウ レンキン T コウゲン ニ タ

Search this article

Description

Activity of lymphocyte transformation (LTF) to streptococcal T antigens was studied in 7 asthmatic children and normal subjects included 21 children and 12 neonates (cord blood).T antigens used were Ti, T4, T6, T8, T12 and T22.<BR>The results are summarized as follows.<BR>1.In unstimulated lymphocyte cultures, no significant difference was found out between asthmatic (mean, 74.9±28.0 cpm) and normal children (mean, 83.5±43.3 cpm) in 3H-thymidine uptake.<BR>2.The LTF activity to these T antigens in asthmatic children was significantly higher than that of normal subjects.The stimulation index (SI), especially, to T12 antigen in asthmatic children (mean SI=132.2) revealed remarkable elevation as compared with that in normal children (mean SI=4.5).

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 59 (9), 846-851, 1985

    The Japanese Association for Infectious Diseases

Keywords

Details 詳細情報について

Report a problem

Back to top