Evaluation of Serological Response to <I>Bartonella henselae</I> by Enzyme Immunoassay in Cat Scratch Disease
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- YOSHIDA Hiroshi
- Department of Medicine, Yame General Hospital
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- KUSABA Nobuhide
- Department of Medicine, Yame General Hospital
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- SUMINO Michihiro
- Department of Medicine, Yame General Hospital
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- SATA Michio
- Second Department of Medicine, Kurume University School of Medicine
Bibliographic Information
- Other Title
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- 猫ひっかき病における酵素抗体法 (EIA) による<I>Bartonellla henselae</I>抗体測定
- Evaluation of Serological Response to Bartonella henselae by Enzyme Immunoassay in Cat Scratch Disease
Abstract
The IgG and IgM titers to Bartonella henselae were determined by an enzyme immunoassay (EIA). The EIA test for detection of IgG and IgM antibodies to B. henselae concerning CSD showed that 8 (40%) of 20 patients with CSD had a serum IgG antibody titer of 12 EIA unit or more and that 5 (25%) patients had a serum IgM titer of 12 EIA unit or more. Totally 12 (60%) of the 20 patients with CSD were seropositive for B. henselae. The mean age of IgG positive patients were higher than IgM positive patients. The IgM antibodies to B. henselae disappeared within 4 to 12 weeks after onset of disease. The IgG antibodies to B. henselae disappeared within 3 to 8 weeks after onset of the symptoms in 2 cases of CSD. Another 2 cases CSD produced high levels of IgG antibodies in the acute phase of the disease. Different course of IgG and IgM antibody titers were found in sera from patients.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 74 (7), 563-566, 2000
The Japanese Association for Infectious Diseases
