播種性血管内凝固症候群 (DIC) を併発した成人のB群髄膜炎菌性髄膜炎の一例

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タイトル別名
  • An Adult Case of Group-B Meningococcal Meningitis Complicated with Disseminated Intravascular Coagulation
  • 播種性血管内凝固症候群(DIC)を併発した成人のB群髄膜炎菌性髄膜炎の1例
  • ハシュセイ ケッカンナイ ギョウコ ショウコウグン DIC オ ヘイハツシタ

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説明

In foreign countries, Neisseria meningitidis occurs bacterial meningitis very often in all age with an incidence from 17 to 56 percent. According to the statistics, an incidence of meningococcal meningitis verying from 30 to 70 percent in bacterial meningitis which causes sepsis complicated with DIC.<BR>In Japan, only 30 or 40 cases are reported every year including adult cases rarely, and a case of meningococcal sepsis complicated with DIC has not reported at all.<BR>Our recent successfull case with meningococcal meningitis complicated with DIC was reported. The patient, 35 years old female, complained general fatigue at first, headache and nausea developed gradually and she fell in confusion at last.<BR>When she was transfered to our hospital, fever, tachycardia and hypotension were noted. On physical examination, there were many petechiae all over the body, sever neck stiffness and Kernig's sign were positive. CSF pressure revealed over 200 mmH20 and liquor was whitish purulent which included 30976/3 cells. Laboratory findings showed severe leukocytosis of 25600/mm3 with left shift, thrombocytopenia, increased FDP, decreased antithrombin III and positive protamine test definitely. And N. meningitidis group B was positive in CSF and blood. The patient was diagnosed to be purulent meningitis and DIC. The therapy was done by intravenous injection of antibiotics (ABPC 16 g/day, CP 8 g/day), steroid hormone, heparin, and FOY® successfully. The patient became disease free 45 days after admission.

収録刊行物

  • 感染症学雑誌

    感染症学雑誌 54 (10), 538-543, 1980

    一般社団法人 日本感染症学会

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