The Clinical Efficacy of Antithrombin III Concentrate in Infections Complicated by DIC

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  • KOBAYASHI Hiroyuki
    The 1st Department of Internal Medicine, Kyorin University, School of Medicine
  • KAWAI Shin
    The 1st Department of Internal Medicine, Kyorin University, School of Medicine
  • OSHITANI Hiroshi
    The 1st Department of Internal Medicine, Kyorin University, School of Medicine
  • TAMAKUMA Shoetsu
    The 1st Department of Surgery, National Defense Medical College
  • HAYASAKA Hiroshi
    The 1st Department of Surgery, Sapporo Medical College
  • AKIYAMA Morio
    The 1st Department of Surgery, Sapporo Medical College
  • NAKAMURA Takashi
    Department of Surgery, Tenshi General Hospital
  • HASHIMOTO Ikuo
    Department of Surgery, Tenshi General Hospital
  • SAWADA Yasuo
    Department of Surgery, Tenshi General Hospital
  • TAKEBE Kazuo
    The 3rd Department of Internal Medicine, School of Medicine, Hirosaki University and Related Hospital
  • OKAMOTO Katsuhiro
    The 3rd Department of Internal Medicine, School of Medicine, Hirosaki University and Related Hospital
  • TAKAHASHI Shuichi
    The 3rd Department of Internal Medicine, School of Medicine, Hirosaki University and Related Hospital
  • MASUDA Mitsuo
    The 3rd Department of Internal Medicine, School of Medicine, Hirosaki University and Related Hospital
  • TAKEDA Hajimu
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • YAMASAKU Fusanosuke
    Department of Internal Medicine, Suibarago Hospital
  • SUZUKI Yasutoshi
    Department of Internal Medicine, Suibarago Hospital
  • KATSU Masataka
    Department of Internal Medicine, Kasumigaura National Hospital
  • HAYASHI Izumi
    Department of Pneumology, Iwaki Municipal Iwaki Public General Hospital
  • ISHIBIKI Kyuya
    Department of Surgery, School of Medicine, Keio University
  • AIKAWA Naoki
    Department of Surgery, School of Medicine, Keio University
  • IKEMOTO Hideo
    Department of Internal Medicine, Juntendo University, School of Medicine
  • WATANABE Kazuyoshi
    Department of Internal Medicine, Juntendo University, School of Medicine
  • HATANO Michinobu
    The 2nd Department of Internal Medicine, Nippon University, School of Medicine
  • SEKI Masato
    The 2nd Department of Internal Medicine, Nippon University, School of Medicine
  • YOSHIDA Sho
    The 2nd Department of Internal Medicine, Chiba University, School of Medicine and Related Hospital
  • WONG Pakming
    The 2nd Department of Internal Medicine, Chiba University, School of Medicine and Related Hospital
  • FUJIMORI Ippei
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • KOBAYASHI Yoshio
    Department of Internal Medicine, Kawasaki Municipal Hospital
  • OHKUBO Takao
    The 1st Department of Internal Medicine, Yokohama City University, School of Medicine
  • MARUTA Ichiro
    The 1st Department of Internal Medicine, Yokohama City University, School of Medicine
  • YURA Jiro
    The 1st Department of Surgery, Nagoya City University, Medical School
  • Ito Minoru
    The 1st Department of Surgery, Nagoya City University, Medical School
  • MISIMA Akira
    The 1st Department of Surgery, Nagoya City University, Medical School
  • TAKEUCHI Toshihiko
    The 1st Department of Internal Medicine, Nagoya City University, Medical School
  • KATO Masahito
    The 1st Department of Internal Medicine, Nagoya City University, Medical School
  • YAMAMOTO Toshiyuki
    Department of Internal Medicine, Nagoya Koseiin Geriatric Hospital
  • KAWAMURA Hidekazu
    Department of Internal Medicine, Nagoya Koseiin Geriatric Hospital
  • SUZUKI Kanzo
    Department of Internal Medicine, Nagoya Koseiin Geriatric Hospital
  • TANIMURA Hiroshi
    The 2nd Department of Surgery, Faculty of Medicine, Kyoto University
  • MORI Keiichiro
    The 2nd Department of Surgery, Faculty of Medicine, Kyoto University
  • SAKAI Katsuji
    The 2nd Department of Surgery, Osaka City University, Medical School
  • UEDA Takami
    The 2nd Department of Surgery, Osaka City University, Medical School
  • FUJIMOTO Mikio
    The 2nd Department of Surgery, Osaka City University, Medical School
  • ORITA Kunzo
    The 1st Department of Surgery, Okayama University, Medical School
  • HAMASAKI Keisuke
    The 1st Department of Surgery, Okayama University, Medical School
  • FUJII Chiiho
    The 2nd Department of Emergency Medicine, Kawasaki Medical School
  • YOKOYAMA Takashi
    The 1st Department of Surgery, Hiroshima University, School of Medicine
  • MIYOSHI Nobukazu
    The 1st Department of Surgery, Hiroshima University, School of Medicine
  • KURIMURA Osamu
    Department of Internal Medicine, Kure National Hospital
  • IHARA Akihiro
    Department of Internal Medicine, Kure National Hospital
  • NAKAYAMA Fumio
    The 1st Department of Surgery, Faculty of Medicine, Kyushu University
  • KAYASHIMA Koji
    The 1st Department of Surgery, Faculty of Medicine, Kyushu University
  • IWASAKI Kazunori
    The 1st Department of Surgery, Faculty of Medicine, Kyushu University
  • SAWAE Yoshiro
    The 1st Department of Internal Medicine, Faculty of Medicine, Kyushu University
  • SHIMURA Hidehiko
    The 1st Department of Surgery, Fukuoka University, School of Medicine
  • TAMAMOTO Hiroshi
    The 1st Department of Surgery, Fukuoka University, School of Medicine
  • HARA Kohei
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • SAITYO Atsushi
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • SHIGENO Yoshiteru
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • YAMAGUCHI Keizo
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • KOHNO Shigeru
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • IZUMIKAWA Kinichi
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • WATANABE Koichi
    The 2nd Department of Internal Medicine, Nagasaki University, School of Medicine and Related Hospital
  • MIYAUCHI Yoshimasa
    The 1st Department of Surgery, Kumamoto University, School of Medicine
  • ITOGA Takashi
    The 2nd Department of Internal Medicine, Medical College of Oita
  • HOSOKAWA Takafumi
    The 2nd Department of Internal Medicine, Medical College of Oita
  • HORI Takashi
    The 2nd Department of Internal Medicine, Medical College of Oita

Bibliographic Information

Other Title
  • 感染症由来DICに対するアンチトロンビンIII濃縮製剤の治療効果に関する研究

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Description

We have assessed the clinical efficacy of AT III concentrate in infections complicated by DIC.<BR>The total number of treated patients amounted to 45.11 patients had to be excluded from the efficacy evaluation.<BR>20 out of the 34 cases that could be analyzed had bleeding symptoms and from these in 14 (70%) cases the bleeding resolved.<BR>The clinical improvement rate was 69.7% and the hematological improvement rate was 81.8%.<BR>If the patients were classified according to the presence or absence of a concomitant medication with Heparin or blood preparations, the following clinical, resp. hematological improvement rates were obtained:<BR>For the group of exclusive administration of AT III: 71.4% resp.85.7% and for the group with concomitant medication: 70.0%, resp. 80.0%.<BR>Side-effects or abnormal laboratory findings that could be attributed to AT III treatment were not observed in any of the 45 cases.<BR>From these results, it can be concluded that AT III concentrate is useful for the treatment of DIC induced by infectious disease.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 59 (11), 1121-1134, 1985

    The Japanese Association for Infectious Diseases

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Details 詳細情報について

  • CRID
    1390001205048882432
  • NII Article ID
    130004329013
  • DOI
    10.11150/kansenshogakuzasshi1970.59.1121
  • COI
    1:STN:280:BimC28bovVQ%3D
  • ISSN
    1884569X
    03875911
    http://id.crossref.org/issn/03875911
  • PubMed
    3938461
  • Article Type
    journal article
  • Data Source
    • JaLC
    • Crossref
    • PubMed
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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