Effect of Oral Colestimide on the Elimination of High-dose Methotrexate in Patients With Primary Central Nervous System Lymphoma-Two Case Reports-

DOI Web Site PubMed 1 Citations 22 References Open Access

Bibliographic Information

Other Title
  • —Two Case Reports—

Search this article

Description

Delayed methotrexate (MTX) elimination occurred in two patients with primary central nervous system lymphoma undergoing high-dose MTX treatment. Oral administration of the anion exchange resin colestimide, which binds MTX effectively in vitro, effectively accelerated MTX elimination. Colestimide probably interrupts the enterohepatic circulation, and is a potential oral antidote to MTX toxicity.<br>

Journal

Citations (1)*help

See more

References(22)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top