Childhood Bacterial Meningitis Trends in Japan from 2007 to 2008
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- SUNAKAWA Keisuke
- Kitasato Institute for Life Science & Graduate School of Infection Control Science, Kitasato University
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- SAKAI Fuminori
- Kitasato Institute for Life Science & Graduate School of Infection Control Science, Kitasato University
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- HIRAO Yuriko
- Kitasato Institute for Life Science & Graduate School of Infection Control Science, Kitasato University
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- HANAKI Hideaki
- Kitasato Institute for Life Science & Graduate School of Infection Control Science, Kitasato University
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- NONOYAMA Masato
- Department of Pediatrics, Ebina General Hospital
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- IWATA Satoshi
- Department of Pediatrics, National Hospital Organization Tokyo Medical Center
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- AKITA Hironobu
- <sup> </sup>Department of Pediatrics, St. Marianna University School of Medicine Yokohama City Seibu Hospital
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- SATO Yoshitake
- Department of Pediatrics, Fuji Heavy Industries LTD. Health Insurance Society Genaral Ota Hospital
Bibliographic Information
- Other Title
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- 本邦における小児細菌性髄膜炎の動向(2007~2008)
- ホンポウ ニ オケル ショウニ サイキンセイ ズイマクエン ノ ドウコウ 2007 2008
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Description
We surveyed pediatrics bacterial meningitis epidemiology from January 2007 to December 2008 in Japan, with the following results : Cases numbered 287-160 male and 127 female-equivalent to 1.54-1.62 of 1,000 pediatric hospitalization per year. Children under 1-year-old accounted for the highest number of cases,which decreased with increasing age. Haemophilus influenzae was the most common cause of infection, followed by Streptococcus pneumoniae, group B streptococcus (GBS), and Escherichia coli. GBS and E. coli were major pathogens in children under 4 months of age, while H. influenzae and S. pneumoniae mainly accounted for those over 4 months of age. Susceptibility tests showed that 51%of H. influenzae isolates and 56.5%of S. pneumoniae isolates in 2008 were drug-resistant. Ampicillin combined with cephem antibiotics effective against GBS, E. coli, and Listeria, were mainly used to initially treat those under 4 months of age. In those over 4 months of age, carbapenem antibiotics are effective against PRSP and cephem antibiotics against H. influenza.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 84 (1), 33-41, 2010
The Japanese Association for Infectious Diseases
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Details 詳細情報について
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- CRID
- 1390001205049840256
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- NII Article ID
- 10026893350
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 10574791
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed