Effectiveness of Oseltamivir Treatment Against Influenza Type A and Type B Infection in Children
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- MITAMURA Keiko
- Department of Pediatrics, Nippon Kokan Hospital
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- SUGAYA Norio
- Department of Pediatrics, Nippon Kokan Hospital
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- NIRASAWA Mari
- Department of Pediatrics, Nippon Kokan Hospital
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- SHINJOH Masayoshi
- Department of Pediatrics, School of Medicine, Keio University
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- TAKEUCHI Yoshinao
- Department of Pediatrics, Kawasaki Municipal Hospital
Bibliographic Information
- Other Title
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- 小児のA型およびB型インフルエンザに対するoseltamivirの効果
- ショウニ ノ Aガタ オヨビ Bガタ インフルエンザ ニ タイスル oseltamivir ノ コウカ
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Abstract
We investigated the effectiveness of oseltamivir treatment against influenza virus infection in children. We treated 131 patients (mean age, 5.8±3.6 years) with oseltamivir (4mg/kg/day for 5 days) during the 200-2002 epidemic. All of the patients had been diagnosed with influenza using a rapid diagnosis kit. When treatment was initiated within 48 hours of the onset of fever, 44%of the patients became afebrile (<37.5°C) within one day, and 86%of them recovered within two days. The average duration of fever after the initiation of oseltamivir treatment was 1.7 days. Oseltamivir was equally effective against both influenza type A and type B. No differences in the effectiveness of oseltamivir treatment were observed between young children (<4 years of age) and school-aged children (>6years of age). No obvious side effects were observed.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 76 (11), 946-952, 2002
The Japanese Association for Infectious Diseases
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Details 詳細情報について
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- CRID
- 1390001205049864192
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- NII Article ID
- 130004331008
- 10010110663
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 6371374
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- PubMed
- 12508478
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed