Effectiveness of Oseltamivir Treatment Against Influenza Type A and Type B Infection in Children

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Other Title
  • 小児のA型およびB型インフルエンザに対するoseltamivirの効果
  • ショウニ ノ Aガタ オヨビ Bガタ インフルエンザ ニ タイスル oseltamivir ノ コウカ

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Abstract

We investigated the effectiveness of oseltamivir treatment against influenza virus infection in children. We treated 131 patients (mean age, 5.8±3.6 years) with oseltamivir (4mg/kg/day for 5 days) during the 200-2002 epidemic. All of the patients had been diagnosed with influenza using a rapid diagnosis kit. When treatment was initiated within 48 hours of the onset of fever, 44%of the patients became afebrile (<37.5°C) within one day, and 86%of them recovered within two days. The average duration of fever after the initiation of oseltamivir treatment was 1.7 days. Oseltamivir was equally effective against both influenza type A and type B. No differences in the effectiveness of oseltamivir treatment were observed between young children (<4 years of age) and school-aged children (>6years of age). No obvious side effects were observed.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 76 (11), 946-952, 2002

    The Japanese Association for Infectious Diseases

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