The Results of an Investigation on the Prevalence Rate of Rubella Antibody, History of Rubella Infection and of Vaccination in Pregnant Women

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  • 妊婦の風疹抗体保有率ならびに風疹ワクチン歴, 既往歴について
  • ニンプ ノ フウシン コウタイ ホユウリツ ナラビニ フウシン ワクチンレキ

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Abstract

The prevalence rate of the rubella antibody in pregnant women was determined and the subjected women were interviewed to investigate their history of rubella, rubella vaccination and acquisition of antibody. In addition, the interval between infection or vaccination and antibody assay, as well as antibody titer, were studied. The subjects comprised 382 pregnant women ranging from 18 years to 42 years old, among whom 301 had acquired the rubella antibody. The prevalence rate was 78.8%. History taking revealed that 149 women (39.0%) had suffered from rubella, 134 (35.1%) not suffered and 99 women (25.9%) could not tell whether they had or not. 47 women (12.3%) had been vaccinated: among them, 21 women received periodic vaccination and 26 were vaccinated occasionally. The relationship between rubella and vaccination history, and antibody acquisition, was studied. The result was that all vaccinated women had acquired the antibody, and 61.2% showed correspondence of rubella history to antibody titer. This suggested that taking history of anamnesis is not reliable in determining whether they experienced rubella or not. An investigation of interval from infection or vaccination to antibody assay showed that the interval ranged from 2 years to 31 years in the group with rubella, and their antibody titers were from 8 times to 256 times higher. In the vaccinated group, the period was 5 months-10 years and titer ranged between 16 times to 128 times higher. Both titers of 2 subjects where there was a lapse of more than 9 years after vaccination were 64 times higher.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 62 (7), 652-656, 1988

    The Japanese Association for Infectious Diseases

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