Use of a Rapid Detection Assay for Influenza Virus, on Nasal Aspirate Specimens

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  • 鼻咽頭吸引液を検体としたOptical Immunoassay法によるインフルエンザ迅速診断
  • ハナ イントウ キュウインエキ オ ケンタイ ト シタ Optical Immunoassayホウ ニ ヨル インフルエンザ ジンソク シンダン

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Abstract

We investigated the usefulness of a rapid antigen detection kit using optical immunoassay for influenza virus (FLU OIA®, BioStar, USA). Nasal aspirates were taken from 92 influenza suspected outpatients between March to April of 1999. Compared with virus isolation and PCR, the sensitivity of FLU OIA ® was 88.5% and 81.6%, and the specificity was 65.2% and 72.2%. All isolated viruses were influenza type B virus. It was difficult to differentiate the weak-positive and negative cases, leading to the rather low specificity, although the assay procedure was easy and quick. FLU OIA ® may be a useful rapid diagnosis kit for influenza in pediatric outpatient clinics and wards, because it can detect both influenza type A and type B viruses.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 73 (10), 1064-1068, 1999

    The Japanese Association for Infectious Diseases

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