A Case of Loiasis

  • SUGIYAMA Etsuro
    Department of Medical Zoology, Faculty of Medicine, Tokyo Medical and Dental University
  • SHINONAGA Satoshi
    Department of Medical Zoology, Faculty of Medicine, Tokyo Medical and Dental University
  • TSUKIDATE Setsuko
    Department of Medical Zoology, Faculty of Medicine, Tokyo Medical and Dental University
  • FUJITA Koichiro
    Department of Medical Zoology, Faculty of Medicine, Tokyo Medical and Dental University
  • NAWATA Hiroko
    First Department of Internal Medicine, Faculty of Medicine, Tokyo Medical and Dental University
  • SAZAKI Nahoko
    First Department of Internal Medicine, Faculty of Medicine, Tokyo Medical and Dental University
  • KAMIKAWADOKO Soichiro
    Department of Ophthalmology, Faculty of Medicine, Tokyo Medical and Dental University
  • OHTAKI Noriko
    Department of Dermatology, Faculty of Medicine, Tokyo Medical and Dental University
  • OKA Keiko
    Department of Dermatology, Faculty of Medicine, Tokyo Medical and Dental University

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Other Title
  • ロア糸状虫症の1症例

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Abstract

We report a case of loiasis which is the second case diagnosed in Japan and is the first case of a Japanese. The patient is a 53-year-old Japanese male who visited Zaire from April to September, 1982. Calabar swelling sometimes appeared on his forearms from about 1984. He suddenly felt right ophthalmalgia on June 1st, 1987 and an adult female of Loa loa was surgically removed under the right bulbar conjunctiva. Microfilaremia was also present (4-5/mm3). The patient was treated with diethylcarbamazine (DEC) under prednisolone and d-chlorpheniramine malate coverage. Treatment was started with a low dose of DEC (6.25mg/day) and the dosage was increased gradually to 300 mg/day in a week and then continued for 3 weeks. A linear skin eruption on the right thigh appeared and an adult female of Loa loa was removed from this region on 7 days after the beginning of DEC treatment. No other severe side reactions were observed. Microfilaremia disappeared 9 days after the beginning of DEC treatment and was also not detected after two months. No recurrence of symptoms nor abnormal findings have been observed for 2 months after DEC treatment.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 62 (5), 490-494, 1988

    The Japanese Association for Infectious Diseases

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