Background Factors and Clinical Course of Patients with Urosepsis
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- SHIMIZU Toshiaki
- Department of Urology, Sapporo Medical University School of Medicine
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- TAKEYAMA Koh
- Department of Urology, Sapporo Medical University School of Medicine
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- YOKOO Akifumi
- Department of Urology, Sapporo Medical University School of Medicine
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- TAKAHASHI Satoshi
- Department of Urology, Sapporo Medical University School of Medicine
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- SATOH Takashi
- Department of Urology, Sapporo Medical University School of Medicine
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- MATSUKAWA Masanori
- Department of Urology, Sapporo Medical University School of Medicine
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- HIROSE Takaoki
- Department of Urology, Sapporo Medical University School of Medicine
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- TSUKAMOTO Taiji
- Department of Urology, Sapporo Medical University School of Medicine
Bibliographic Information
- Other Title
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- Urosepsis症例の背景因子と臨床経過
- Urosepsis ショウレイ ノ ハイケイ インシ ト リンショウ ケイカ
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Description
In this study, we analyzed background factors and clinical courses of31patients having 32 episodes of urosepsis, which was defined as the disease when the same species of bacteria were simultaneously isolated both from urine and blood in a febrile (≥38°C) patient. Most of the patients had a malignant disease. These patients were classified into3groups by febrile patterns, based on [responder], [partial responder] and [non-responder]. [non-responder] was one in which fever persisted for more than7days. Background factors such as those of bacteria and host were compared among the three groups. Pseudomonas aeruginosa was more frequently isolated from both urine and blood of patients having not only the [responder] but also the [non-responder]. Patients having the [responder] and [partia responder] had a higher frequency of isolation of Escherichia coli (E. coli) from urine and blood, suggesting that urosepsis caused by E. coli may respond more easily to antimicrobial chemotherapy. While the direct cause of urosepsis was not identified in 6 patients, manipulations of the urinary tract were a direct cause of the disease in all 26 other patients. An indwelling catheter in the central vein or urinary tract alone did not influence the clinical courses of patients. However, when patients with respiratory or renal dysfunction, or a cerebrovascular accident had an indwelling catheter, the urosepsis was intractable for antibacterial chemotherapy. Antimicrobial chemotherapy using a single agent was effective in all patients having the [responder]. Combination chemotherapy or alternation of agents was eventually needed for treatment in more than half of the patients with the [partial responder] or [non-responder]. No patients died from the disease.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 73 (7), 652-657, 1999
The Japanese Association for Infectious Diseases
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Keywords
Details 詳細情報について
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- CRID
- 1390001205050686080
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- NII Article ID
- 130004112701
- 10008716061
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- NII Book ID
- AN00047715
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- COI
- 1:STN:280:DyaK1MvhtFSitg%3D%3D
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 4788412
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- PubMed
- 10481400
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed