Discrepancy Between [18F]fluorodeoxyglucose and 11C-methionine Positron Emission Tomography Findings in Sturge-Weber Syndrome -Case Report-

DOI Web Site PubMed 2 Citations 22 References Open Access
  • ICHINOSE Tsutomu
    Department of Neurosurgery, Osaka City University Graduate School of Medicine
  • TSUYUGUCHI Naohiro
    Department of Neurosurgery, Osaka City University Graduate School of Medicine
  • MORINO Michiharu
    Department of Neurosurgery, Osaka City University Graduate School of Medicine
  • SUNADA Ichiro
    Department of Neurosurgery, Saiseikai Ibaragi Hospital
  • OHATA Kenji
    Department of Neurosurgery, Osaka City University Graduate School of Medicine
  • TAKAMI Toshihiro
    Department of Neurosurgery, Osaka City University Graduate School of Medicine
  • SHIMONISHI Yoshihiro
    Department of Nuclear Medicine, Osaka City University Graduate School of Medicine
  • KAWABE Joji
    Department of Nuclear Medicine, Osaka City University Graduate School of Medicine
  • SHIOMI Susumu
    Department of Nuclear Medicine, Osaka City University Graduate School of Medicine
  • HARA Mitsuhiro
    Department of Neurosurgery, Osaka City University Graduate School of Medicine

Bibliographic Information

Other Title
  • —Case Report—

Search this article

Description

Cerebral blood flow and metabolism were evaluated in an adult with symptomatic intractable epilepsy and Sturge-Weber syndrome (SWS) manifesting as angiomas in the left cerebral hemisphere. 99mTc-ethylcysteinate dimer single photon emission computed tomography detected reduced blood flow in the entire left cerebral hemisphere, and [18F]fluorodeoxyglucose positron emission tomography (PET) showed decreased glucose metabolism in the left cerebral hemisphere. These findings indicated hypofunction of the left cerebral hemisphere, which caused the right hemiparesis. 11C-methionine (11C-Met) PET revealed high 11C-Met accumulation in the angiomas in the left cerebral hemisphere. Immunostaining for glial fibrillary acidic protein showed positive reaction in the lesions. Gliosis is a likely mechanism for the 11C-Met accumulation, which is possibly associated with progressive calcification in the angiomas and retarded growth of patients with SWS occurring over many years.<br>

Journal

Citations (2)*help

See more

References(22)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top