A COMPARATIVE STUDY ASSESSING CLINICAL EFFECTS OF NAFTOPIDIL AND TAMSULOSIN HYDROCHLORIDE ON BENIGN PROSTATIC HYPERPLASIA WITH OVERACTIVE BLADDER
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- Kosugi Shigeru
- Department of Urology Jikei University School of Medicine
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- Ikemoto Isao
- Department of Urology Jikei University School of Medicine
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- Furuta Akira
- Department of Urology Jikei University School of Medicine
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- Shimomura Tatsuya
- Department of Urology Jikei University School of Medicine
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- Kiyota Hiroshi
- Department of Urology Jikei University School of Medicine
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- Suzuki Yasuyuki
- Department of Urology Jikei University School of Medicine
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- Kishimoto Kouichi
- Department of Urology Jikei University School of Medicine
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- Egawa Shin
- Department of Urology Jikei University School of Medicine
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- Torii Shinichiro
- Torii Clinic
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- Shirai Hitoshi
- Midori Clinic
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- Takeuchi Hiroyuki
- Shinyuri-Takeuchi Clinic
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- Abe Kazuhiro
- Shinyuri-Takeuchi Clinic
Bibliographic Information
- Other Title
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- 過活動膀胱を伴った前立腺肥大症症例に対するナフトピジルと塩酸タムスロシンとの治療効果の比較検討
- カカツドウ ボウコウ オ トモナッタ ゼンリツセン ヒダイショウ ショウレイ ニ タイスル ナフトピジル ト エンサン タムスロシン トノ チリョウ コウカ ノ ヒカク ケントウ
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Abstract
(Purpose) We compared the efficacy of naftopidil with that of tamsulosin hydrochloride for 154 symptomatic benign prostatic hyperplasia (BPH) patients who also suffered from over active bladder (OAB) symptoms.<br>(Materials and methods) Naftopidil and tamsulosin hydrochloride were administered for eight weeks. The international prostate symptom score (IPSS), QOL index, maximum flow rate (Qmax), residual urine volume (RUV) and side effect profile were determined before the administration and after eight weeks of treatment.<br>(Results) In the naftopidil group, seven parameters of IPSS and QOL index were improved significantly at the endpoint compared to the baseline. In the tamsulosin group, all parameters except frequency and straining were also improved. Both drugs improved the Qmax at the endpoint, too. The RUV did not change in both groups. Naftopidil was also superior to tamsulosin hydrochloride regarding general treatment outcome by the Japanese clinical guideline of urinary disturbance.<br>(Conclusions) This study demonstrated that naftopidil was clinically efficacious in the treatment of BPH patients with OAB.
Journal
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- The Japanese Journal of Urology
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The Japanese Journal of Urology 98 (5), 691-699, 2007
THE JAPANESE UROLOGICAL ASSOCIATION
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Details 詳細情報について
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- CRID
- 1390001205055470080
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- NII Article ID
- 110006345439
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- NII Book ID
- AN00196577
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- ISSN
- 18847110
- 00215287
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- NDL BIB ID
- 8896097
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed