A CASE OF ADVANCED NON-SEMINOMATOUS TESTICULAR GERM CELL TUMOR ACCOMPANIED PANIC DISORDER
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- Okumura Akiou
- Department of Urology, Kurobe City Hospital
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- Morii Akihiro
- Department of Urology, Kurobe City Hospital
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- Kiriyama Masato
- Department of Surgical Medicine, Kurobe City Hospital
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- Takamatsu Hideyuki
- Department of Internal Medicine, Kurobe City Hospital
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- Shimizu Masashi
- Department of Nuclear Medicine, Kurobe City Hospital
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- Yasui Shinichi
- Department of Psychiatry, Kurobe City Hospital
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- Takagawa Kiyoshi
- Department of Pathology, Kurobe City Hospital
Bibliographic Information
- Other Title
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- パニック障害を有する進行性非セミノーマの1例
- 症例報告 パニック障害を有する進行性非セミノーマの1例
- ショウレイ ホウコク パニック ショウガイ オ ユウスル シンコウセイ ヒセミノーマ ノ 1レイ
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Abstract
<p>We report a 33-year-old male with a left advanced non-seminomatous testicular germ cell tumor (NSGCT) accompanied panic disorder. He had experienced palpitation and hyperpnea in crowds in his twenties. He was admitted to the Department of Otorhinolaryngology with the chief complaint of left neck swelling. 18F-fluorodeoxy glucose positron emission tomography/computed tomography (FDG-PET/CT) demonstrated left neck, left supraclavicular, left axillary, and paraaortic lymph node (LN) swelling and left testicular swelling. He was referred to our department. The left testis had enlarged to the size of a fist. He rejected admission at that time, but next day, he was taken to our hospital by an ambulance because he lost consciousness at home. No abnormalities were found in the brain CT and electrocardiogram. He was admitted and left high orchiectomy was performed. The human chorionic gonadotropin (HCG) level had elevated to 9,717 IU/L and alpha fetoprotein level (AFP) had elevated to 427 ng/ml. The histopathological diagnosis was tumors of more than one histological type, mixed forms: seminoma and embryonal carcinoma.</p><p>He had palpitation and hyperpnea after admission and was diagnosed with panic disorder by a psychiatrist. Psychotropic drugs (fluvoxamine maleate 50 mg/day, alprazolam 0.8 mg/day) were prescribed and the panic attacks disappeared afterwards. The psychiatric social worker supported his mind side. Bleomycin, etoposide, and cisplatin (BEP) therapy was performed for 4 courses. He put on a blanket to his face and came to avoid a conversation with other people during the chemotherapy. He was diagnosed with depression and psychotropic drugs were increased (fluvoxamine maleate 50→75 mg/day, alprazolam 0.8→1.2 mg/day) in quantity.</p><p>Lymphadenectomies for LN metastases were performed and their histopathological examination revealed the existence of viable embryonal carcinoma in the supraclavicular LN. Etoposide, ifosfamide, and cisplatin (VIP) therapy was performed for 2 courses.</p><p>The pateint has remained alive without tumor recurrence. Psychotropic drugs were reduced and the recent drug is fluvoxamine maleate 25 mg/day.</p>
Journal
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- The Japanese Journal of Urology
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The Japanese Journal of Urology 107 (1), 48-53, 2016
THE JAPANESE UROLOGICAL ASSOCIATION
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Keywords
Details 詳細情報について
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- CRID
- 1390001205056222592
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- NII Article ID
- 130005298653
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- NII Book ID
- AN00196577
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- ISSN
- 18847110
- 00215287
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- NDL BIB ID
- 027051325
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- PubMed
- 28132992
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed