USEFULNESS OF EXTENSION OF DISEASE AS A PROGNOSTIC FACTOR IN RELAPSED PROSTATE CANCER PATIENTS OF STAGE D

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  • Kawai Masaki
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Uemura Hiroji
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Hasumi Hisashi
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Osada Yutaka
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Ohta Jun-ichi
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Miyoshi Yasuhide
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Mikata Kunihisa
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Oh-uchi Hideki
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Sugiura Shinpei
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Fujinami Kiyoshi
    Department of Urology, Yokohama City University Graduate School of Medicine
  • Kubota Yoshinobu
    Department of Urology, Yokohama City University Graduate School of Medicine

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Other Title
  • 再燃前立腺癌 Stage D症例における予後因子としてのEOD分類の有用性
  • サイネン ゼンリツセンガン Stage D ショウレイ ニ オケル ヨゴ インシ ト シテ ノ EOD ブンルイ ノ ユウヨウセイ

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(Objective) The prognosis of prostate cancer has been evaluated by clinical stage or pathological grade. PSA parameters including PSA density and PSA doubling time have not always precisely reflected the prognosis of prostate cancer. The aim of this study was to evaluate PSA parameters and extension of disease (EOD) grade as prognostic factors for relapsed prostate cancer.<br>(Methods) The relationship between PSA parameters or EOD grade, and survival of 29 stage D patients with relapsed prostate cancer after initial hormone therapy was examined.<br>(Results) Only EOD grade was an independent prognostic factor, even for cause-specific survival period and survival period after relapse.<br>(Conclusion) EOD grade was a significant prognostic factor, and in particular, very useful as a prognostic factor for patients with bone metastasis. PSA value was not always associated with tumor volume, and therefore it is not an independent prognostic factor.

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