A Case of Rapid Exacerbation of Pulmonary <i>Mycobacterium Avium</i> Complex Infection Mimicking Pulmonary Aspergillosis

  • NOGUCHI Shingo
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan Department of Respiratory Medicine, Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan
  • YATERA Kazuhiro
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • YAMASAKI Kei
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • KAWANAMI Toshinori
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • TAKAHASHI Toru
    Department of Hematology, Yamaguchi Grand Medical Center, Japan
  • SHIMABUKURO Ikuko
    Department of Respiratory Medicine, Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan
  • AKATA Kentarou
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • ISHIMOTO Hiroshi
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan
  • FUJII Takashi
    Department of Cardiovascular Medicine, Yamaguchi Grand Medical Center, Japan
  • YOSHII Chiharu
    Department of Respiratory Medicine, Wakamatsu Hospital of the University of Occupational and Environmental Health, Japan
  • MUKAE Hiroshi
    Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan

Bibliographic Information

Other Title
  • 肺アスペルギルス症との鑑別に苦慮し,急性増悪をきたした肺<i>Mycobacterium avium </i>complex感染症の1例
  • 肺アスペルギルス症との鑑別に苦慮し,急性増悪をきたした肺Mycobacterium avium complex感染症の1例
  • A Case of Rapid Exacerbation of Pulmonary Mycobacterium Avium Complex Infection Mimicking Pulmonary Aspergillosis

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Description

We herein report a case of pulmonary Mycobacterium avium complex (MAC) infection with pulmonary multiple nodules and the “halo sign” on chest computed tomography (CT) in which the patient showed rapid exacerbation seven years after undergoing bone marrow transplantation (BMT). A 68-year-old Japanese female visited our hospital due to a productive cough and dyspnea. She had undergone allogeneic BMT for acute myelocytic leukemia and received both prednisolone (2 mg/day) and cyclosporine (30 mg/day). Chest CT demonstrated no abnormal findings on admission; however, multiple pulmonary nodules and the “halo sign” were detected three weeks later. Although a fungal infection was initially suspected, a bronchoscopic examination revealed pulmonary MAC infection. In the present case, pulmonary MAC infection exhibited rapid progression with unique CT findings. Physicians should consider MAC infection in the differential diagnosis in patients who receive BMT and/or immunosuppressive agents, even if the clinical and radiological findings are atypical of the disease.

Journal

  • Journal of UOEH

    Journal of UOEH 37 (3), 177-183, 2015

    The University of Occupational and Environmental Health, Japan

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