T1-weighted Magnetic Resonance Imaging Sequence Appropriate for the Evaluation of the Longitudinal Relaxation Effect of Superparamagnetic Iron Oxide: A Phantom Study.
-
- Takahama Katsuya
- Department of Radiology, Nippon Medical School
-
- Amano Yasuo
- Department of Radiology, Nippon Medical School
-
- Hayashi Hiromitsu
- Department of Radiology, Nippon Medical School
-
- Kumazaki Tatsuo
- Department of Radiology, Nippon Medical School
この論文をさがす
説明
The goal of this study was to determine a T1-weighted magnetic resonance (MR) imaging sequence appropriate for evaluating the longitudinal relaxation effect of superparamagnetic iron oxide (ferumoxides) in a phantom study. An agarose phantom that included various concentrations of ferumoxides (0∼0.5 mmol/l in 0.05 mmol/l increments) was examined for six types of T1-weighted imaging sequences using a 1.5-T MR unit. Three-dimensional (3D) fast spoiled gradient-echo (SPGR) imaging with a short echo time showed a strong linear correlation between the concentration of ferumoxides and the enhancement ratio. Two-dimensional (2D) fast SPGR imaging showed a high signal-to-noise ratio of the phantom even at low ferumoxides concentrations. These results suggest that 3D fast SPGR imaging is an appropriate technique for the evaluation of the longitudinal relaxation effect of ferumoxides, and that 2D fast SPGR imaging can be useful for evaluating the longitudinal relaxation effect at lower ferumoxides concentrations.
収録刊行物
-
- 日医大誌
-
日医大誌 69 (6), 571-576, 2002
日本医科大学医学会