Metabolic Syndrome and Heart Failure

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  • Miura Yutaka
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Fukumoto Yoshihiro
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Shiba Nobuyuki
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Miura Toshiro
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Shimada Kazunori
    Department of Cardiovascular Medicine, Juntendo University School of Medicine
  • Iwama Yoshitaka
    Department of Cardiovascular Medicine, Juntendo University School of Medicine
  • Takagi Atsutoshi
    Department of Cardiovascular Medicine, Juntendo University School of Medicine
  • Matsusaka Hidenori
    Division of Cardiovascular Medicine, Aso-Iizuka Hospital
  • Tsutsumi Takaki
    Division of Cardiovascular Medicine, Aso-Iizuka Hospital
  • Yamada Akira
    Division of Cardiovascular Medicine, Aso-Iizuka Hospital
  • Kinugawa Shintaro
    Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
  • Asakura Masanori
    Cardiovascular Division of Internal Medicine, National Cerebral and Cardiovascular Center
  • Okamatsu Shuichi
    Division of Cardiovascular Medicine, Aso-Iizuka Hospital
  • Tsutsui Hiroyuki
    Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
  • Daida Hiroyuki
    Department of Cardiovascular Medicine, Juntendo University School of Medicine
  • Matsuzaki Masunori
    Division of Cardiology, Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine
  • Tomoike Hitonobu
    Cardiovascular Division of Internal Medicine, National Cerebral and Cardiovascular Center
  • Shimokawa Hiroaki
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine

書誌事項

タイトル別名
  • Prevalence and Clinical Implication of Metabolic Syndrome in Chronic Heart Failure - Report From MetS-CHF Study -
  • – Report From MetS-CHF Study –

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説明

Background: Metabolic syndrome (MetS) is a pathological condition with a clustering of metabolic components and is a well-known risk and prognostic factor for ischemic heart disease (IHD). However, the prevalence and clinical significance of MetS remain to be fully elucidated in chronic heart failure (CHF), an important clinical syndrome caused by various cardiac abnormalities. Methods and Results: The present nationwide, large-scale clinical study enrolled 3,603 patients with stage C/D CHF from 6 institutes in Japan. First, the prevalence of MetS in CHF patients was demonstrated to be 45% in males and 19% in females, which is more than double compared with the general population in Japan. The CHF patients with MetS were characterized by younger age, higher prevalence of current smoking and drinking, IHD, and hypertensive heart disease, whereas the prevalence of HF with preserved ejection fraction and MetS was higher in elderly female patients. Next, the contribution of the metabolic components (waist circumference, hypertension, glucose intolerance/diabetes mellitus and dyslipidemia) was found to be comparable between the ischemic and the non-ischemic CHF patients. Conclusions: The prevalence of MetS in CHF patients is more than double compared with the general population in Japan and suggest that the metabolic components may have a substantial effect on the development of both ischemic and non-ischemic CHF. (Circ J 2010; 74: 2612-2621)<br>

収録刊行物

  • Circulation Journal

    Circulation Journal 74 (12), 2612-2621, 2010

    一般社団法人 日本循環器学会

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