Metabolic syndrome over four years before the onset of cardiovascular disease: nested case-control Study
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- Hu Huanhuan
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Nakagawa Tohru
- Hitachi, Ltd.
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- Honda Toru
- Hitachi, Ltd.
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- Yamamoto Shuichiro
- Hitachi, Ltd.
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- Nanri Akiko
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Konishi Maki
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Okazaki Hiroko
- Mitsui Chemicals, Inc.
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- Kuwahara Keisuke
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine Teikyo University Graduate School of Public Health
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- Hori Ai
- Department of Global Public Health, University of Tsukuba
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- Nishiura Chihiro
- Tokyo Gas Co., Ltd.
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- Kashino Ikuko
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Imai Teppei
- Azbil Corporation
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- Nishihara Akiko
- Azbil Corporation
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- Akter Shamima
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Miyamoto Toshiaki
- Nippon Steel & Sumitomo Metal Corporation Kimitsu Works
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- Sasaki Naoko
- Mitsubishi Fuso Truck and Bus Corporation
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- Ogasawara Takayuki
- Mitsubishi Fuso Truck and Bus Corporation
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- Uehara Akihiko
- Seijinkai Shizunai Hospital
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- Yamamoto Makoto
- YAMAHA CORPORATION
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- Murakami Taizo
- Mizue Medical Clinic, Keihin Occupational Health Center
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- Shimizu Makiko
- Mizue Medical Clinic, Keihin Occupational Health Center
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- Eguchi Masafumi
- Furukawa Electric Co., Ltd.
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- Kochi Takeshi
- Furukawa Electric Co., Ltd.
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- Nagahama Satsue
- All Japan Labour Welfare Foundation
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- Tomita Kentaro
- Mitsubishi Plastics, Inc.
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- Kabe Isamu
- Furukawa Electric Co., Ltd.
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- Mizoue Tetsuya
- Department of Epidemiology and Prevention, National Center for Global Health and Medicine
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- Sone Tomofumi
- National Institute of Public Health
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- Dohi Seitaro
- Mitsui Chemicals, Inc.
書誌事項
- タイトル別名
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- Metabolic Syndrome Over 4 Years Before the Onset of Cardiovascular Disease ― Nested Case-Control Study ―
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説明
<p>Background:We investigated the risk of cardiovascular disease (CVD) with duration of metabolic syndrome (MetS) for the past 4 years before the CVD event.</p><p>Methods and Results:We performed a nested case-control study within the Japan Epidemiology Collaboration on Occupational Health Study. A total of 139 registered cases of CVD and 561 self-reported cases of CVD were identified and matched individually on age, sex, and worksite with 695 and 2,803 controls, respectively. MetS was defined by the Joint Interim Statement definition. The odds ratio (95% confidence interval) for registered CVD was 4.7 (2.9, 7.5) for people with persistent MetS (positive for MetS for ≥3 assessments) and 1.9 (1.1, 3.3) for those with intermittent MetS (positive for MetS for 1–2 assessments), compared with people without MetS during the past 4 years before the event/index date (P for trend <0.001). The corresponding odds ratio for self-reported CVD was 2.7 (2.2, 3.5) and 1.8 (1.4, 2.3) (P for trend <0.001). The association with MetS duration was stronger for myocardial infarction than for other CVD subtypes. Similar results were obtained when using the Japanese MetS criteria.</p><p>Conclusions:The risk of CVD increases with increasing MetS duration. These findings contribute to risk stratification and encourage lifestyle modification for people with MetS to minimize their health risk.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 82 (2), 430-436, 2018
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205106204032
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- NII論文ID
- 130006321868
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 028782115
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- PubMed
- 28931789
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- 本文言語コード
- en
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- JaLC
- NDL
- Crossref
- PubMed
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