Feasibility of Optical Coronary Tomography in Quantitative Measurement of Coronary Arteries With Lipid-Rich Plaque
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- Kubo Takashi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Yamano Takashi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Liu Yong
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Ino Yasushi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Shiono Yasutsugu
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Orii Makoto
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Taruya Akira
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Nishiguchi Tsuyoshi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Shimokado Aiko
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Teraguchi Ikuko
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Tanimoto Takashi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Kitabata Hironori
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Yamaguchi Tomoyuki
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Hirata Kumiko
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Tanaka Atsuhi
- Department of Cardiovascular Medicine, Wakayama Medical University
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- Akasaka Takashi
- Department of Cardiovascular Medicine, Wakayama Medical University
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Abstract
Background:The aim of the present study was to evaluate the feasibility of optical coherence tomography (OCT) for measurement of vessel area in coronary arteries with lipid-rich plaque as compared with intravascular ultrasound (IVUS).Methods and Results:We investigated 80 coronary artery segments with lipid-rich plaque on OCT and non-attenuated plaque on IVUS. According to the lipid arc on OCT, the plaques were classified into 4 groups: group 1, lipid arc ≤90°; group 2, 90°<lipid arc≤180°; group 3, 180°<lipid arc≤270°; group 4, lipid arc >270°. Vessel circular arcs that could not be identified due to OCT signal attenuation were interpolated using an approximating algorithm. OCT-measured vessel area was well-correlated with IVUS-measured vessel area (R=0.834, P<0.001). On Bland-Altman plot, there was a good agreement between OCT-measured vessel area and IVUS-measured vessel area, although mean difference and limits of agreement increased with increase of lipid arc (mean difference in groups 1–4: –0.21, –0.31, –1.02, and –2.13 mm2; lower limit: –1.49, –3.22, –5.24, and –9.25 mm2; and upper limit: 1.07, 2.60, 3.20, and 4.99 mm2). Intra-observer (R=0.97–0.99, P<0.001) and inter-observer (R=0.97–0.99, P<0.001) reproducibility for OCT measurement of vessel area was excellent.Conclusions:Like IVUS, OCT can be used to measure vessel area in coronary arteries with lipid-rich plaque. (Circ J 2015; 79: 600–606)
Journal
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- Circulation Journal
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Circulation Journal 79 (3), 600-606, 2015
The Japanese Circulation Society
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Details 詳細情報について
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- CRID
- 1390001205107036288
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- NII Article ID
- 130004927118
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- NII Book ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL BIB ID
- 026187091
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- PubMed
- 25492038
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed