Prediction of Chronic Vessel Enlargement by a Novel Intravascular Ultrasound Finding : Peri-Medial High-Echoic Band

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  • Prediction of Chronic Vessel Enlargement by a Novel Intravascular Ultrasound Finding
  • – Peri-Medial High-Echoic Band –

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Background:Coronary arterial segments distal to the severely stenotic lesion sometimes shrink as a result of decreased coronary flow. Pathological studies have shown that vessel shrinkage is accompanied by folding of the internal elastic membrane (IEM). A peri-medial high-echoic band (PHB) by intravascular ultrasound (IVUS) may represent folding of the IEM and therefore detect chronically shrunken coronary segments that have potential to enlarge subsequently.Methods and Results:IVUS imaging of the distal reference segments was performed in 27 patients after stenting. PHB was defined as a high-echoic band observed at the luminal side of the media. Serial (baseline and 9 months) changes in minimal lumen diameter (LD) were compared between those with (PHB group) and without PHB (non-PHB group). During follow-up, LD increased significantly in PHB group (1.2±0.3 vs. 1.7±0.5 mm, P=0.001) but not in the non-PHB group (2.0±0.7 vs. 2.1±0.7 mm, P=NS). Late lumen gain (LLG) was observed in 16 of the 27 (59%) lesions. Lesions with LLG showed a trend toward smaller baseline lumen cross-sectional area and significantly higher prevalence of PHB (88% vs. 18%, P=0.007). By multivariable logistic regression analysis, PHB was the only IVUS predictor of LLG.Conclusions:Presence of PHB on IVUS predicts chronic enlargement of the coronary segments distal to the stented lesion. (Circ J 2015; 79: 607–612)

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  • Circulation Journal

    Circulation Journal 79 (3), 607-612, 2015

    一般社団法人 日本循環器学会

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