Long-Term Clinical Outcomes of True and Non-True Bifurcation Lesions According to Medina Classification – Results From the COBIS (COronary BIfurcation Stent) II Registry –
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- Park Taek Kyu
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Park Yong Hwan
- Samsung Changwon Hospital, Sungkyunkwan University School of Medicine
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- Song Young Bin
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Oh Ju Hyeon
- Samsung Changwon Hospital, Sungkyunkwan University School of Medicine
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- Chun Woo Jung
- Samsung Changwon Hospital, Sungkyunkwan University School of Medicine
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- Kang Gu Hyun
- Samsung Changwon Hospital, Sungkyunkwan University School of Medicine
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- Jang Woo Jin
- Samsung Changwon Hospital, Sungkyunkwan University School of Medicine
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- Hahn Joo-Yong
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Yang Jeong Hoon
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Choi Seung-Hyuk
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Choi Jin-Ho
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Lee Sang Hoon
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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- Jeong Myung-Ho
- Chonnam National University Hospital
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- Kim Hyo-Soo
- Seoul National University Hospital
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- Lee Jae-Hwan
- Chungnam National University Hospital
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- Yu Cheol Woong
- Korea University Anam Hospital
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- Rha Seung Woon
- Korea University Guro Hospital
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- Jang Yangsoo
- Yonsei University Severance Hospital
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- Yoon Jung Han
- Wonju Christian Hospital
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- Tahk Seung-Jea
- Ajou University Hospital
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- Seung Ki Bae
- Catholic University Kangnam St. Mary’s Hospital
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- Park Jong-Seon
- and Yeungnam University Hospital
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- Gwon Hyeon-Cheol
- Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine
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説明
Background:Little is known about the clinical outcomes of patients with different types of coronary bifurcation lesions. We sought to compare long-term clinical outcomes of patients with true or non-true bifurcation lesions who underwent percutaneous coronary intervention.Methods and Results:We compared major adverse cardiac events (MACE: cardiac death, myocardial infarction [MI], or target lesion revascularization) between 1,502 patients with true bifurcation lesions (51.8%) and 1,395 with non-true bifurcation lesions (48.2%). True bifurcation lesions were defined as Medina classification (1.1.1), (1.0.1), or (0.1.1) lesions. During a median follow-up of 36 months, MACE occurred in 296 (10.2%) patients. Patients with true bifurcation lesions had a significantly higher risk of MACE than those with non-true bifurcation lesions (HR 1.39; 95% CI 1.08–1.80; P=0.01). Among true bifurcation lesions, Medina (1.1.1) and (0.1.1) were associated with a higher risk of cardiac death or MI than Medina (1.0.1) (HR 4.15; 95% CI 1.01–17.1; P=0.05). During the procedure, side branch occlusion occurred more frequently in Medina (1.1.1) and (1.0.1) than Medina (0.1.1) lesions (11.5% vs. 7.4%, P=0.03).Conclusions:Patients with true bifurcation lesions had worse clinical outcomes than those with non-true bifurcation lesions. Procedural and long-term clinical outcomes differed according to the type of bifurcation lesion. These findings should be considered in future bifurcation studies. (Circ J 2015; 79: 1954–1962)
収録刊行物
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- Circulation Journal
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Circulation Journal 79 (9), 1954-1962, 2015
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205107811456
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- NII論文ID
- 130005095312
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 026690339
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- PubMed
- 26134457
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
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- PubMed
- CiNii Articles
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- 使用不可