Impact of Catheter Ablation for Paroxysmal Atrial Fibrillation in Patients With Sick Sinus Syndrome – Important Role of Non-Pulmonary Vein Foci –
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- Hayashi Kentaro
- Department of Cardiology, Kokura Memorial Hospital
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- Fukunaga Masato
- Department of Cardiology, Kokura Memorial Hospital
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- Yamaji Kyohei
- Department of Cardiology, Kokura Memorial Hospital
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- An Yoshimori
- Department of Cardiology, Kokura Memorial Hospital
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- Nagashima Michio
- Department of Cardiology, Kokura Memorial Hospital
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- Hiroshima Kenichi
- Department of Cardiology, Kokura Memorial Hospital
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- Ohe Masatsugu
- Department of Cardiology, Kokura Memorial Hospital
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- Makihara Yu
- Department of Cardiology, Kokura Memorial Hospital
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- Yamashita Kennosuke
- Department of Cardiology, Kokura Memorial Hospital
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- Ando Kenji
- Department of Cardiology, Kokura Memorial Hospital
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- Iwabuchi Masashi
- Department of Cardiology, Kokura Memorial Hospital
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- Goya Masahiko
- Department of Cardiology, Kokura Memorial Hospital
Bibliographic Information
- Other Title
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- Impact of catheter ablation for paroxysmal atrial fibrillation in patients with sick sinus syndrome
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Abstract
Background:The clinical efficacy of catheter ablation (CA) for paroxysmal atrial fibrillation (PAF) in patients with sick sinus syndrome (SSS) and the mechanism and predictors of recurrence are not yet completely elucidated.Methods and Results:Of 963 consecutive patients who underwent PAF ablation during the study period, a total of 108 patients with SSS (SSS group) and 108 matched controls without SSS (non-SSS group) were followed up. During the follow-up period (mean, 32.8±17.5 months), the SSS group had significantly higher AF recurrence rate since the last procedure than the non-SSS group (26.9% vs. 12.0%; P=0.02). The SSS group had significantly higher prevalence of non-pulmonary vein (non-PV) foci than the non-SSS group (25.9% vs. 13.9%; P=0.027). On multivariate analysis congestive heart failure (HR, 13.7; 95% CI: 1.57–119; P=0.02) and non-PV foci (HR, 5.75; 95% CI: 1.69–19.6; P=0.005) were independent predictors of recurrence following CA in the SSS group. In the SSS group, 88 patients had bradycardia-tachycardia syndrome without prior permanent pacemaker implantation. Of these, 6 required pacemaker implantation because of AF and sinus pause recurrence.Conclusions:Patients with SSS are at higher risk of AF recurrence after CA. Non-PV foci are associated with AF recurrence following PAF with SSS. (Circ J 2016; 80: 887–894)
Journal
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- Circulation Journal
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Circulation Journal 80 (4), 887-894, 2016
The Japanese Circulation Society
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Keywords
Details 詳細情報について
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- CRID
- 1390001205109033984
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- NII Article ID
- 130005139556
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- NII Book ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL BIB ID
- 027203012
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- PubMed
- 26936115
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed